The Chemical Compositions of Essential Oils Derived from Cryptocarya alba and Laurelia sempervirens Possess Antioxidant, Antibacterial and Antitumoral Activity Potential
Autor
Touma, Jorge
Navarro, Myriam
Sepúlveda, Bestabet
Pavón, Alequis
Corsini, Gino
Fernández, Katia
Quezada, Claudia Andrea
Torres, Ángelo
Larrazabal-Fuentes, María José
Paredes, Adrián
Neira, Iván
Ferrando, Matías
Bruna, Flavia
Venegas, Alejandro
Bravo, Jessica
Resumen
Cryptocarya alba (Peumo; CA) and Laurelia sempervirens (Laurel; LS) are herbs native to the Chilean highlands and have historically been used for medicinal purposes by the Huilliches people. In this work, the essential oils were extracted using hydrodistillation in Clevenger apparatus and analyzed by GC-MS to determine their composition. The antioxidant capacity (AC) was evaluated in vitro. The cytotoxicity was determined using cell line cultures both non tumoral and tumoral. The toxicity was determined using the nematode Caenorhabditis elegans. The antimicrobial activity was evaluated against 52 bacteria using the agar disc diffusion method and the minimum inhibitory concentrations (MICs) were determined. The principal compounds found in C. alba essential oil (CA_EO) were α-terpineol (24.96%) and eucalyptol (21.63%) and were isazafrol (91.9%) in L. sempervirens essential oil (LS_EO). Both EOs showed antioxidant capacity in vitro. Both EO showed antibacterial activity against bacteria using. LS_EO showed more inhibitory effect on these cell lines respect to CA_EO. Both EOs showed toxicity against the nematode C.elegans at 3.12-50 mg/mL. The essential oils of CA and LS have an important bioactive potential in their antioxidant, antibacterial and cytotoxicity activity. Both essential oils could possibly be used in the field of natural medicine, natural food preservation, cosmetics, sanitation and plaguicides among others.
Colecciones
Ítems relacionados
Mostrando ítems relacionados por Título, autor o materia.
-
Article
In vitro Cytotoxicity of the Antimicrobial Polypeptide Nisin on Blood Tumor Cells (2024)
Salazar, Lorena; Rivas, Elizabeth; Pavón, Alequis; Wiese, Guillermo; Manzano, Camila; Orellana, Paz; Gutierrez-Moraga, Ana; Cortés-Cortés, Piedad; Corsini, Gino (Universidad de la Frontera, 2022)Bacteriocins are antimicrobial peptides of ribosomal synthesis secreted by bacteria. Among these, nisin stands out, which has potential uses in antibiotic therapies, as a food bio preservative and probiotics. Nisin has ... -
Article
Eugenol supplementation as an additive to improve the thermal stability of Hedychium coronarium Koening essential oil (2020)
Macias J.P.J.; Castro R.I.; Esguerra S.K.G.; Marin J.G.; Guzman L.; Gutierrez M.; Vergara C.E.; Forero-Doria O. (Bentham Science Publishers, 2020) -
Article
Analysis of the Zonula occludens Toxin Found in the Genome of the Chilean Non-toxigenic Vibrio parahaemolyticus Strain PMC53.7 (2020)
Pérez-Reytor, Diliana Celeste; Pavón, Alequis; López-Joven, Carmen; Ramírez-Araya, Sebastián; Peña-Varas, Carlos; Plaza, Nicolás; Alegría-Arcos, Melissa; Corsini, Gino; Jaña, Víctor; Pavez, Leonardo; ... (Frontiers Media S.A., 2020-09-24)Vibrio parahaemolyticus non-toxigenic strains are responsible for about 10% of acute gastroenteritis associated with this species, suggesting they harbor unique virulence factors. Zonula occludens toxin (Zot), firstly ...