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Hydroxy-3-Phenylcoumarins as Multitarget Compounds for Skin Aging Diseases: Synthesis, Molecular Docking and Tyrosinase, Elastase, Collagenase and Hyaluronidase Inhibition, and Sun Protection Factor (2024)
(MDPI, 2022)Skin aging is a progressive biological process of the human body, and it is not only time-dependent. Differently substituted 3-phenylcoumarins proved to efficiently inhibit tyrosinase. In the current work, new substitution ... -
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Hydroxyapatite-based magnetic bionanocomposite as pharmaceuticals carriers in chitosan scaffolds (2021)
(MDPI AG, 2021)Hydroxyapatite (HA) is a bioceramic very similar to the mineral component of bones and teeth. It is well established that osteoblasts grow better onto HA-coated metals than on metals alone. Herein, the preparation of a new ... -
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Hydroxybenzoic acid derivatives as dual-target ligands: Mitochondriotropic antioxidants and cholinesterase inhibitors (2020)
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Hyperplastic sensory corpuscles in nevus sebaceus of labia minora pudendi. A case report (2020)
(Blackwell Publishing Ltd, 2018) -
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Hypertensive Nephropathy: Unveiling the Possible Involvement of Hemichannels and Pannexons (2024)
(MDPI, 2022)Hypertension is one of the most common risk factors for developing chronic cardiovascular diseases, including hypertensive nephropathy. Within the glomerulus, hypertension causes damage and activation of mesangial cells ... -
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I Justify Myself, Therefore I am. Regimes Of Justification In Chilean Elite Universities (2024)
(Hipatia Editorial, 2024)Few studies focus on understanding the role of universities in the elites’ legitimation processes. This article examines how elite universities-in the context of Chilean tertiary education massification-actively create ... -
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‘I'm still a woman’: A qualitative study on sexuality in heterosexual women with Turner Syndrome (2024)
(John Wiley and Sons Inc, 2023)Aim and objectives: The aim of this study was to describe and understand how heterosexual women with Turner Syndrome experience sexuality. Background: Turner Syndrome is a genetic condition that is the result of one of the ... -
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Ibuprofen intake increases exercise time to exhaustion: A possible role for preventing exercise-induced fatigue (2020)
(Blackwell Munksgaard, 2016) -
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Ideal Cardiovascular Health and Arterial Stiffness in Spanish Adults—The EVIDENT Study (2020)
(W.B. Saunders, 2018) -
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Identification and specificity validation of unique and antimicrobial resistance genes to trace suspected pathogenic AMR bacteria and to monitor the development of AMR in non-AMR strains in the environment and clinical settings (2024)
(Elsevier B.V., 2023)The detection of developing antimicrobial resistance (AMR) has become a global issue. The detection of developing antimicrobial resistance has become a global issue. The growing number of AMR bacteria poses a new threat ... -
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Identification and validation of new reference genes for accurate quantitative reverse transcriptase-PCR normalization in the Antarctic plant Colobanthus quitensis under abiotic stress conditions (2021)
(Springer Science and Business Media Deutschland GmbH, 2021-02-02)The Antarctic ecotype of Colobanthus quitensis is a vascular plant highly adapted to the harsh environmental conditions of Maritime Antarctica which is now facing with the rapid local warming experienced in the Antarctic ... -
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Identification of a critical binding site for local anaesthetics in the side pockets of Kv1 channels (2021)
(John Wiley and Sons Inc, 2021)Background and Purpose: Local anaesthetics block sodium and a variety of potassium channels. Although previous studies identified a residue in the pore signature sequence together with three residues in the S6 segment as ... -
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Identification of a Family of Vibrio Type III Secretion System Effectors That Contain a Conserved Serine/Threonine Kinase Domain (2021)
(NLM (Medline), 2021-08-25)Vibrio parahaemolyticus is a marine Gram-negative bacterium that is a leading cause of seafood-borne gastroenteritis. Pandemic strains of V. parahaemolyticus rely on a specialized protein secretion machinery known as the ... -
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Identification of Antarctic Soil Bacteria Exhibiting Antiproliferative Activity Against a Colon Cancer Cell Line (2024)
(Universidad de la Frontera, 2023)Cancer is the second leading cause of death in the world and colorectal cancer is the only cancer that has shown a sustained increase in mortality in the last decade. In the search for new chemotherapeutic agents against ... -
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Identification of Circulating lncRNAs Associated with Gallbladder Cancer Risk by Tissue-Based Preselection, Cis-eQTL Validation, and Analysis of Association with Genotype-Based Expression (2022)
(MDPI, 2022-02-01)Long noncoding RNAs (lncRNAs) play key roles in cell processes and are good candi-dates for cancer risk prediction. Few studies have investigated the association between individual genotypes and lncRNA expression. Here we ... -
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Identification of coexisting indigo species in an ancient green thread using direct plasmon-enhanced Raman spectroscopy (2020)
(Sociedad Chilena de Quimica, 2020-06-30)A green ancient thread sample from a Chilean mummy turban was analyzed by plasmon-enhanced Raman scattering spectroscopy using a direct drop-colloidal method. The enhanced-Raman signals in the sample are associated with ... -
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Identification of Critical Residues in the Carboxy Terminus of the Dopamine Transporter Involved in the G Protein βγ-Induced Dopamine Efflux (2021)
(Frontiers Media S.A., 2021-03-24)The dopamine transporter (DAT) plays a crucial role in the regulation of brain dopamine (DA) homeostasis through the re-uptake of DA back into the presynaptic terminal. In addition to re-uptake, DAT is also able to release ... -
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Identification of learning needs in Early Childhood Bachelor students (2024)
(AUFOP, 2023)The objective of the study was to know the impact of the components on the teaching and learning processes of students of early childhood careers in Chile. To achieve this objective, a quantitative, non-experimental, ...