Mentally-passive sedentary behavior and incident depression: Mediation by inflammatory markers
Autor
Werneck, André O.
Owen, Neville
Araujo, Raphael H.O.
Silva, Danilo R.
Hallgren, Mats
Resumen
Background: Sedentary behavior (SB; time spent sitting, as distinct from lack of exercise or physical activity) is associated with depression, yet little is known about the relationship between different types of SB (e.g., mentally-passive versus mentally-active) with depression and potential biological mediators of these associations. Methods: We used cohort data from the 1958 National Child Development Study (n = 4607; 50.4 % women), conducted in UK, employing the 44 y and 46 y waves as baseline, and the 50 y and 55 y waves as follow-up. Participants reported time spent in TV viewing and watching videos (mentally-passive SB); and, time sitting while doing light activities such as deskwork or driving a car during worktime (mentally-active SB). Depression diagnosis was self-reported during the initial and follow-up waves. Waist circumference, C-reactive protein, and glycated hemoglobin were examined as potential mediators. Results: Mentally-passive SB was associated with incident depression (HR: 1.43; 95%CI: 1.19; 1.71), while there was no association for mentally-active SB. Waist circumference (coefficient: −0.03; 95%CI: −0.05; −0.01; 9.2 %) and C-reactive protein (coefficient: −0.03; 95%CI: −0.04; −0.01; 8.3 %), but not glycated hemoglobin, partly mediated the association for mentally-passive SB. Conclusions: In the relationship of mentally-passive SB with incident depression, the mediating contributions of waist circumference and C-reactive protein point to possible inflammatory-related mechanisms. © 2023 The Author(s)
Colecciones
Ítems relacionados
Mostrando ítems relacionados por Título, autor o materia.
-
Physical Activity and Sitting Time Patterns and Sociodemographic Correlates Among 155,790 South American Adults (2024)
Werneck, Andre O.; Araujo, Raphael H. O.; Anza-Ramirez, Cecilia; Brazo-Sayavera, Javier; Garcia-Witulski, Christian; Aguilar-Farias, Nicolas; Baldew, Se-Sergio; Sadarangani, Kabir P.; Ramirez-Velez, Robinson; Garcia-Hermoso, Antonio; ... (HUMAN KINETICS PUBL INC, 2023)Background: To estimate the prevalence of different physical activity (PA) domains and sitting time (ST), and to analyze the association with sociodemographic indicators. Methods: Data from the most recent nationally ... -
Article
Sociodemographic inequalities in the trends of different types of leisure-time physical activity among Brazilian adults between 2006 and 2019 (2024)
Araujo, Raphael H. O.; Werneck, André O.; Silva, Danilo R.; Jesus, Gilmar M. (BioMed Central Ltd, 2022)Background: The current study aimed to describe the trends in gender, ethnicity, and education inequalities of types of leisure-time physical activity (LTPA) practiced by Brazilian adults from 2006 to 2019. Methods: We ... -
Article
Physical activity intervention (Movi-Kids) on improving academic achievement and adiposity in preschoolers with or without attention deficit hyperactivity disorder: Study protocol for a randomized controlled trial (2020)
Sánchez-López M.; Pardo-Guijarro M.J.; del Campo D.G.-D.; Silva P.; Martínez-Andrés M.; Gulías-González R.; Díez-Fernández A.; Franquelo-Morales P.; Martínez-Vizcaíno V.; Mota J.; ... (BioMed Central Ltd., 2015)