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The role of B cells in COVID-19 infection and vaccination
dc.contributor.author | Chen, Shiru | |
dc.contributor.author | Guan, Fei | |
dc.contributor.author | Candotti, Fabio | |
dc.contributor.author | Benlagha, Kamel | |
dc.contributor.author | Camara, Niels Olsen Saraiva | |
dc.contributor.author | Herrada, Andres A. | |
dc.contributor.author | James, Louisa K. | |
dc.contributor.author | Lei, Jiahui | |
dc.contributor.author | Miller, Heather | |
dc.contributor.author | Kubo, Masato | |
dc.contributor.author | Ning, Qin | |
dc.contributor.author | Liu, Chaohong | |
dc.date.accessioned | 2024-04-10T06:36:08Z | |
dc.date.available | 2024-04-10T06:36:08Z | |
dc.date.issued | 2022 | |
dc.identifier | 10.3389/fimmu.2022.988536 | |
dc.identifier.issn | 16643224 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12728/11029 | |
dc.description.abstract | B cells secrete antibodies and mediate the humoral immune response, making them extremely important in protective immunity against SARS-CoV-2, which caused the coronavirus disease 2019 (COVID-19) pandemic. In this review, we summarize the positive function and pathological response of B cells in SARS-CoV-2 infection and re-infection. Then, we structure the immunity responses that B cells mediated in peripheral tissues. Furthermore, we discuss the role of B cells during vaccination including the effectiveness of antibodies and memory B cells, viral evolution mechanisms, and future vaccine development. This review might help medical workers and researchers to have a better understanding of the interaction between B cells and SARS-CoV-2 and broaden their vision for future investigations. Copyright © 2022 Chen, Guan, Candotti, Benlagha, Camara, Herrada, James, Lei, Miller, Kubo, Ning and Liu. | es_ES |
dc.description.sponsorship | HUST Academic Frontier Youth Team, (2018QYTD10); National Natural Science Foundation of China, NNSFC, NNSF, NSF, NSFC; China Postdoctoral Science Foundation | es_ES |
dc.language.iso | en | es_ES |
dc.publisher | Frontiers Media S.A. | es_ES |
dc.subject | antibody | es_ES |
dc.subject | B cells | es_ES |
dc.subject | COVID-19 | es_ES |
dc.subject | memory B cells | es_ES |
dc.subject | SARS-CoV-2 | es_ES |
dc.subject | vaccination | es_ES |
dc.title | The role of B cells in COVID-19 infection and vaccination | es_ES |
dc.type | Article | es_ES |