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dc.contributor.authorSaz-Lara, Alicia
dc.contributor.authorÁlvarez-Bueno, Celia
dc.contributor.authorSolera-Martínez, Montserrat
dc.contributor.authorNotario-Pacheco, Blanca
dc.contributor.authorSequí-Dominguez, Irene
dc.contributor.authorCavero-Redondo, Iván
dc.date.accessioned2020-09-28T14:47:59Z
dc.date.available2020-09-28T14:47:59Z
dc.date.issued2020-09-02
dc.identifier10.3390/ijerph17186936
dc.identifier.issn16617827
dc.identifier.urihttps://hdl.handle.net/20.500.12728/6915
dc.description.abstractEvidence exists regarding the association between advanced glycation end products and different cardiovascular disease subclinical processes, such as arterial stiffness and atherosclerosis. With this systematic review and meta-analysis, we aimed to provide a synthesis of the evidence regarding the association of arterial stiffness measured by pulse wave velocity and atherosclerosis measured by carotid intima media thickness with skin autofluorescence. A systematic search was performed using: MEDLINE (PubMed), SCOPUS, and Web of Science, until 30 March 2020. Cross-sectional studies or baseline data from prospective longitudinal studies were considered. The DerSimonian and Laird method was used to calculate the pooled estimates of correlation coefficients and the corresponding 95% confidence intervals (CI) for the association of pulse wave velocity and carotid intima media thickness with skin autofluorescence. Twenty-five studies were included in the systematic review and meta-analysis, including 6306 subjects. The pooled correlation coefficient was 0.25 (95% CI: 0.18, 0.31) for pulse wave velocity and skin autofluorescence, and 0.31 (95% CI: 0.25, 0.38) for carotid intima media thickness and skin autofluorescence. This systematic review and meta-analysis provide a synthesis of the evidence showing a positive weak association of pulse wave velocity and carotid intima media thickness with skin autofluorescence.es_ES
dc.language.isoenes_ES
dc.publisherMDPI AGes_ES
dc.subjectAdvanced glycation end productses_ES
dc.subjectArterial stiffnesses_ES
dc.subjectCardiovascular diseasees_ES
dc.subjectCarotid intima media thicknesses_ES
dc.subjectPulse wave velocityes_ES
dc.subjectSkin autofluorescencees_ES
dc.titleAre advanced glycation end products in skin associated with vascular dysfunction markers? A meta-analysises_ES
dc.typeArticlees_ES


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