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dc.contributor.authorSingh S.K.
dc.contributor.authorBarreto G.E.
dc.contributor.authorAliev G.
dc.contributor.authorEcheverria V.
dc.date.accessioned2020-09-02T22:28:18Z
dc.date.available2020-09-02T22:28:18Z
dc.date.issued2017
dc.identifier10.2174/1389200217666161201112206
dc.identifier.citation18, 2, 112-119
dc.identifier.issn13892002
dc.identifier.urihttps://hdl.handle.net/20.500.12728/6269
dc.descriptionBackground: Mental disorders are the most common health problems in the worldwide population. Current medicines against these conditions have undesired side effects or limited effectiveness. These disadvantageous pharmacological and therapeutic characteristics provoke a low adherence to treatment in an important percentage of patients with mental disorders. Since ancient times, ethnically different groups have been using plants extracts as medicines for the treatment of mental conditions including dementia, depression and anxiety disorders. Among them are extracts of Ginkgo biloba, a tree in the division Gingophyta, that has been used by millions of people worldwide. Objective: This review aims to discuss current scientific evidence of efficacy, neuroprotective and antioxidant effects as mechanism of action, side effects and potential interaction with other commonly prescribed anxiolytic drugs. Methods: A PubMed search of preclinical studies as well as individual clinical trials and meta-analysis were scrutinized. Results: Various preclinical and clinical studies have shown a positive effect of Ginkgo biloba to improve cognitive abilities in impaired individuals and reducing anxiety under pathological conditions. Conclusion: A more advanced clinical research is needed to confirm the efficacy of Gingko biloba for the treatment of anxiety in different health conditions. © 2017 Bentham Science Publishers.
dc.language.isoen
dc.publisherBentham Science Publishers B.V.
dc.subjectAlzheimer
dc.subjectAnxiety
dc.subjectMedicinal plants
dc.subjectNeurodegeneration
dc.subjectNeuroinflammation
dc.subjectOxidative stress
dc.subjectaripiprazole
dc.subjectbenzodiazepine derivative
dc.subjectbuspirone
dc.subjectGinkgo biloba extract
dc.subjectquetiapine
dc.subjectrisperidone
dc.subjectanxiolytic agent
dc.subjectGinkgo biloba extract
dc.subjectplant extract
dc.subjectalternative medicine
dc.subjectAlzheimer disease
dc.subjectantioxidant activity
dc.subjectattention deficit disorder
dc.subjectbrain hemorrhage
dc.subjectbrain ischemia
dc.subjectcognition
dc.subjectcognitive behavioral therapy
dc.subjectcognitive defect
dc.subjectdelusion
dc.subjectdementia
dc.subjectdepression
dc.subjectdizziness
dc.subjectdrug efficacy
dc.subjectdrug safety
dc.subjectgastrointestinal symptom
dc.subjectgeneralized anxiety disorder
dc.subjectGinkgo biloba
dc.subjectheadache
dc.subjecthuman
dc.subjectintraocular hemorrhage
dc.subjectmental disease
dc.subjectmental health
dc.subjectmeta analysis (topic)
dc.subjectmultiple sclerosis
dc.subjectnervous system inflammation
dc.subjectneuroprotection
dc.subjectneurotransmission
dc.subjectpleiotropy
dc.subjectprevalence
dc.subjectrandomized controlled trial (topic)
dc.subjectReview
dc.subjectschizophrenia
dc.subjectskin allergy
dc.subjectskin irritation
dc.subjectsystematic review (topic)
dc.subjectanimal
dc.subjectdementia
dc.subjectmental disease
dc.subjectphytotherapy
dc.subjectAnimals
dc.subjectAnti-Anxiety Agents
dc.subjectDementia
dc.subjectHumans
dc.subjectMental Disorders
dc.subjectPhytotherapy
dc.subjectPlant Extracts
dc.titleGinkgo biloba as an alternative medicine in the treatment of anxiety in dementia and other psychiatric disorders
dc.typeReview


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