Healing of burns type AB-B in guinea pig (Cavia porcellus) using ulmo honey associated with oral Vitamin C [Cicatrización en quemaduras tipo AB-B en conejillo de indias (Cavia porcellus) utilizando miel de ulmo asociada a Vitamina C oral]
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del Sol M.
In recent years there has been increasing interest in the use of alternative therapies for healing wounds. Bee honey is an ancient natural medicine that has been used in the treatment of wounds and ulcers, while Vitamin C improves the epidermal barrier and reduces wound contraction. The aim of this study is to support treatment with honey associated with oral vitamin C as an alternative and efficient healing treatment, in type AB-B burns. For this study, twelve guinea pigs (Cavia porcellus) were used. The animals were distributed in groups A (without Vitamin C) and B (with Vitamin C). While under anesthetic effect burn of 1.7 mm in diameter was caused in the right dorsal region, subsequent healing was treated with honey. At the same time a burn of similar characteristics was caused in the left dorsal region, treated with Ringer serum being used as control. Biopsies were obtained from both lesions at days 6, 10 and 14 post injury. Results showed granulartissue formation, fibroblast activation, and reepitalization is more rapid in group B, where vascularized tissue and organized collagen fibers were observed at day 14 post injury similar to control (biopsy in healthy animal). These results confirm that the use of Ulmo honey associated with oral Vitamin C improves regeneration in this type of wound, achieving effective, rapid and good quality healing.
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Comparative study of healing in burns treatment based on ulmo honey (Eucryphia cordifolia) and oral vitamin C in guinea pig (Cavia porcellus) versus hydrogel [Estudio comparativo de la cicatrización en quemaduras con tratamiento en base a miel de Ulmo (Eucryphia cordifolia) y vitamina C oral versus hidrogel en cobayos (Cavia porcellus).] (2020) Schencke C.; Salvo J.; Vasconcellos A.; del Sol M. (2013)
Renal Stereology in the Guinea Pig (Cavia porcellus) [Estereología Renal en el Cobayo (Cavia porcellus)] (2020) Barrera Zapata J.L.; del Sol M.; Vásquez B. (Universidad de la Frontera, 2009)