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dc.contributor.authorPérez-Reytor D.
dc.contributor.authorPlaza N.
dc.contributor.authorEspejo R.T.
dc.contributor.authorNavarrete P.
dc.contributor.authorBastías R.
dc.contributor.authorGarcia K.
dc.date.accessioned2020-09-02T22:26:26Z
dc.date.available2020-09-02T22:26:26Z
dc.date.issued2017
dc.identifier10.3389/fmicb.2016.02160
dc.identifier.citation7, JAN, -
dc.identifier.issn1664302X
dc.identifier.urihttps://hdl.handle.net/20.500.12728/5911
dc.descriptionIn recent decades, the identification of small non-coding RNAs in bacteria has revealed an important regulatory mechanism of gene expression involved in the response to environmental signals and to the control of virulence. In the family Vibrionaceae, which includes several human and animal pathogens, small non-coding RNAs (sRNAs) are closely related to important processes including metabolism, quorum sensing, virulence, and fitness. Studies conducted in silico and experiments using microarrays and high-throughput RNA sequencing have led to the discovery of an unexpected number of sRNAs in Vibrios. The present review discusses the most relevant reports regarding the mechanisms of action of sRNAs and their implications in the virulence of the main human pathogens in the family Vibrionaceae: Vibrio parahaemolyticus, V. vulnificus and V. cholerae. © 2017 Pérez-Reytor, Plaza, Espejo, Navarrete, Bastías and Garcia.
dc.language.isoen
dc.publisherFrontiers Media S.A.
dc.subjectBioinformatics analysis
dc.subjectPathogenic vibrios
dc.subjectQuorum sensing
dc.subjectSRNA
dc.subjectVibrio cholerae
dc.subjectVibrio parahaemolyticus
dc.subjectVibrio vulnificus
dc.subjectVirulence
dc.subjectbacterial protein
dc.subjectbacterial RNA
dc.subjectchaperone
dc.subjectHfq protein
dc.subjectRyhB RNA
dc.subjectsmall untranslated RNA
dc.subjectSpot 42 RNA
dc.subjectToxT activated RNA A
dc.subjectToxT activated RNA B
dc.subjectunclassified drug
dc.subjectVibrio regulatory RNA of OmpA
dc.subject5' untranslated region
dc.subjectbacterial gene
dc.subjectbacterial metabolism
dc.subjectbacterial virulence
dc.subjectbioinformatics
dc.subjectCRISPR Cas system
dc.subjectgene control
dc.subjectgene expression
dc.subjectgene sequence
dc.subjectgenetic transcription
dc.subjecthuman
dc.subjectiron metabolism
dc.subjectnonhuman
dc.subjectquorum sensing
dc.subjectReview
dc.subjectVibrio
dc.subjectVibrio cholerae
dc.subjectVibrio parahaemolyticus
dc.subjectVibrio vulnificus
dc.titleRole of non-coding regulatory RNA in the virulence of human pathogenic vibrios
dc.typeReview


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