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dc.contributor.authorMurga I.
dc.contributor.authorGuillen V.
dc.contributor.authorLafuente J.-V.
dc.date.accessioned2020-09-02T22:24:10Z
dc.date.available2020-09-02T22:24:10Z
dc.date.issued2017
dc.identifier10.1016/j.medcli.2017.01.034
dc.identifier.citation148, 11, 511-516
dc.identifier.issn00257753
dc.identifier.urihttps://hdl.handle.net/20.500.12728/5526
dc.descriptionFibromyalgia syndrome is a chronic disease, of unknown origin, whose diagnostic criteria were established in 1990 by the American College of Rheumatology. New criteria were proposed in 2010 that have not yet been validated. It is characterized by a generalized chronic musculoskeletal pain, accompanied by hyperalgesia and allodynia, as well as other motor, vegetative, cognitive and affective symptoms and signs. We have reviewed a set of studies with cerebral magnetic resonance (morphometry, connectivity and spectroscopy) that refer to changes in areas involved in pain processing. Modifications in gray and white matter volume, as well as in levels of N-acetylaspartate, choline or glutamate, among other metabolites, have been observed in the hippocampus, insula, prefrontal and cingular cortex. Neuroradiological findings are nonspecific and similar to those found in other examples of chronic pain. An increase in the sample size and a standardized methodology would facilitate comparison, allowing the drawing of general conclusions. © 2017 Elsevier España, S.L.U.
dc.language.isoen
dc.language.isoes
dc.publisherEdiciones Doyma, S.L.
dc.subjectBrain magnetic resonance
dc.subjectConnectivity
dc.subjectFibromyalgia syndrome
dc.subjectMorphometry
dc.subjectSpectroscopy
dc.subjectcholine
dc.subjectglutamic acid
dc.subjectn acetylaspartic acid
dc.subjectbrain size
dc.subjectchronic pain
dc.subjectcingulate gyrus
dc.subjectcomparative study
dc.subjectfibromyalgia
dc.subjectgray matter
dc.subjecthippocampus
dc.subjecthuman
dc.subjectinsula
dc.subjectmorphometry
dc.subjectneuroimaging
dc.subjectneuroradiology
dc.subjectnuclear magnetic resonance imaging
dc.subjectnuclear magnetic resonance spectroscopy
dc.subjectprefrontal cortex
dc.subjectReview
dc.subjectwhite matter
dc.subjectbrain
dc.subjectdiagnostic imaging
dc.subjectfibromyalgia
dc.subjectneuroimaging
dc.subjectBrain
dc.subjectFibromyalgia
dc.subjectHumans
dc.subjectMagnetic Resonance Imaging
dc.subjectNeuroimaging
dc.titleCerebral magnetic resonance changes associated with fibromyalgia syndrome [Cambios en la resonancia magnética cerebral asociados al síndrome de fibromialgia]
dc.typeReview


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