Curcumin as a therapeutic agent in leukemia
MetadataShow full item record
Leukemia comprises a group of hematological malignancies responsible for 8% of all cancers and is the most common cancer in children. Despite significant improvements in leukemia treatment, the efficacy of conventional chemotherapeutic agents is low and the disease carries a poor prognosis with frequent relapses and high mortality. Curcumin is a yellow polyphenol compound with diverse pharmacological actions including anticancer, antioxidant, antidiabetic, anti-inflammatory, immunomodulatory, hepatoprotective, lipid-regulating, antidepressant, and antiarthritic. Many cellular and experimental studies have reported the benefits of curcumin in treating leukemia. Curcumin's anticancer effects are exerted via various mechanisms. Here, we review the effects of curcumin on various types of leukemia whilst considering its mechanisms of action. © 2019 Wiley Periodicals, Inc.
Showing items related by title, author, creator and subject.
ReviewGhasemi F.; Bagheri H.; Barreto G.E.; Read M.I.; Sahebkar A. (Springer New York LLC, 2019)
Modulatory effects of curcumin on heat shock proteins in cancer: A promising therapeutic approach (2020) Forouzanfar F.; Barreto G.; Majeed M.; Sahebkar A. (Blackwell Publishing Inc., 2019)
Curcumin as a therapeutic candidate for multiple sclerosis: Molecular mechanisms and targets (2020) Ghanaatian N.; Lashgari N.-A.; Abdolghaffari A.H.; Rajaee S.M.; Panahi Y.; Barreto G.E.; Butler A.E.; Sahebkar A. (Wiley-Liss Inc., 2019)