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dc.contributor.authorKeshavarzi Z.
dc.contributor.authorShakeri F.
dc.contributor.authorBarreto G.E.
dc.contributor.authorBibak B.
dc.contributor.authorSathyapalan T.
dc.contributor.authorSahebkar A.
dc.date.accessioned2020-09-02T22:21:07Z
dc.date.available2020-09-02T22:21:07Z
dc.date.issued2019
dc.identifier10.1002/biof.1516
dc.identifier.citation45, 4, 517-535
dc.identifier.issn09516433
dc.identifier.urihttps://hdl.handle.net/20.500.12728/5001
dc.descriptionTraumatic brain injury (TBI) is the most prevalent health problem affecting all age groups, and leads to many secondary problems in other organs especially kidneys, gastrointestinal tract, and heart function. In this review, the search terms were TBI, fluid percussion injury, cold injury, weight drop impact acceleration injury, lateral fluid percussion, cortical impact injury, and blast injury. Studies with Actaea racemosa, Artemisia annua, Aframomum melegueta, Carthamus tinctorius, Cinnamomum zeylanicum, Crocus sativus, Cnidium monnieri, Curcuma longa, Gastrodia elata, Malva sylvestris, Da Chuanxiong Formula, Erigeron breviscapus, Panax ginseng, Salvia tomentosa, Satureja khuzistanica, Nigella sativa, Drynaria fortune, Dracaena cochinchinensis, Polygonum cuspidatum, Rosmarinus officinalis, Rheum tanguticum, Centella asiatica, and Curcuma zedoaria show a significant decrease in neuronal injury by different mechanisms such as increasing superoxide dismutase and catalase activities, suppressing nuclear factor kappa B (NF-κB), interleukin 1 (IL-1), glial fibrillary acidic protein, and IL-6 expression. The aim of this study was to evaluate the neuroprotective effects of medicinal plants in central nervous system pathologies by reviewing the available literature. © 2019 International Union of Biochemistry and Molecular Biology
dc.language.isoen
dc.publisherBlackwell Publishing Inc.
dc.subjectbrain
dc.subjectmedicinal plants
dc.subjectsignaling mechanisms
dc.subjectTBI
dc.subjecttrauma
dc.subjectActaea racemosa extract
dc.subjectAframomum melegueta extract
dc.subjectArtemisia annua extract
dc.subjectcatalase
dc.subjectCentella asiatica extract
dc.subjectCinnamomum zeylanicum extract
dc.subjectCnidium monnieri extract
dc.subjectCrocus sativus extract
dc.subjectCurcuma longa extract
dc.subjectCurcuma zedoaria extract
dc.subjectda chuanxiong
dc.subjectDracaena cochinchinensis extract
dc.subjectDrynaria fortune extract
dc.subjectErigeron breviscapus extract
dc.subjectGastrodia elata extract
dc.subjectginseng extract
dc.subjectglial fibrillary acidic protein
dc.subjectimmunoglobulin enhancer binding protein
dc.subjectinterleukin 1
dc.subjectinterleukin 6
dc.subjectMalva sylvestris extract
dc.subjectNigella sativa extract
dc.subjectplant medicinal product
dc.subjectPolygonum cuspidatum extract
dc.subjectRheum tanguticum extract
dc.subjectRosmarinus officinalis extract
dc.subjectsafflower extract
dc.subjectSalvia tomentosa extract
dc.subjectSatureja khuzistanica extract
dc.subjectsuperoxide dismutase
dc.subjectunclassified drug
dc.subjectcatalase
dc.subjectglial fibrillary acidic protein
dc.subjectglial fibrillary astrocytic protein, mouse
dc.subjectimmunoglobulin enhancer binding protein
dc.subjectinterleukin 1
dc.subjectinterleukin 6
dc.subjectinterleukin-6, mouse
dc.subjectneuroprotective agent
dc.subjectsuperoxide dismutase
dc.subjectActaea racemosa
dc.subjectAframomum melegueta
dc.subjectArtemisia annua
dc.subjectblack cumin
dc.subjectblast injury
dc.subjectCentella asiatica
dc.subjectCinnamomum zeylanicum
dc.subjectCnidium monnieri
dc.subjectcold injury
dc.subjectCrocus sativus
dc.subjectCurcuma longa
dc.subjectCurcuma zedoaria
dc.subjectcytokine release
dc.subjectDracaena cochinchinensis
dc.subjectdrug formulary
dc.subjectdrug mechanism
dc.subjectDrynaria fortune
dc.subjectErigeron breviscapus
dc.subjectGastrodia elata
dc.subjectginseng
dc.subjectMalva sylvestris
dc.subjectmedicinal plant
dc.subjectneuroprotection
dc.subjectnonhuman
dc.subjectPolygonum cuspidatum
dc.subjectpriority journal
dc.subjectReview
dc.subjectRheum tanguticum
dc.subjectrosemary
dc.subjectsafflower
dc.subjectSalvia tomentosa
dc.subjectSatureja khuzistanica
dc.subjecttraumatic brain injury
dc.subjectanimal
dc.subjectblast injury
dc.subjectbrain cortex
dc.subjectchemistry
dc.subjectcold injury
dc.subjectdisease model
dc.subjectdrug effect
dc.subjectgene expression regulation
dc.subjectgenetics
dc.subjecthuman
dc.subjectinjury
dc.subjectisolation and purification
dc.subjectmedicinal plant
dc.subjectmetabolism
dc.subjectmouse
dc.subjectpathology
dc.subjectrat
dc.subjecttraumatic brain injury
dc.subjectAnimals
dc.subjectBlast Injuries
dc.subjectBrain Injuries, Traumatic
dc.subjectCatalase
dc.subjectCerebral Cortex
dc.subjectCold Injury
dc.subjectDisease Models, Animal
dc.subjectGene Expression Regulation
dc.subjectGlial Fibrillary Acidic Protein
dc.subjectHumans
dc.subjectInterleukin-1
dc.subjectInterleukin-6
dc.subjectMice
dc.subjectNeuroprotective Agents
dc.subjectNF-kappa B
dc.subjectPlants, Medicinal
dc.subjectRats
dc.subjectSuperoxide Dismutase
dc.titleMedicinal plants in traumatic brain injury: Neuroprotective mechanisms revisited
dc.typeReview


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