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dc.contributor.authorGonzález-Ruíz K.
dc.contributor.authorCorrea-Bautista J.E.
dc.contributor.authorIzquierdo M.
dc.contributor.authorGarcía-Hermoso A.
dc.contributor.authorDominguez-Sanchez M.A.
dc.contributor.authorBustos-Cruz R.H.
dc.contributor.authorGarcía-Prieto J.C.
dc.contributor.authorMartínez-Vizcaíno V.
dc.contributor.authorLobelo F.
dc.contributor.authorGonzález-Jiménez E.
dc.contributor.authorPrieto-Benavides D.H.
dc.contributor.authorTordecilla-Sanders A.
dc.contributor.authorSchmidt-RioValle J.
dc.contributor.authorPerez G.
dc.contributor.authorRamírez-Vélez R.
dc.date.accessioned2020-09-02T22:19:24Z
dc.date.available2020-09-02T22:19:24Z
dc.date.issued2018
dc.identifier10.1186/s13063-018-2721-5
dc.identifier.citation19, 1, -
dc.identifier.issn17456215
dc.identifier.urihttps://hdl.handle.net/20.500.12728/4731
dc.descriptionBackground: A considerable proportion of contemporary youth have a high risk of obesity-related disorders such as cardiovascular disease, metabolic syndrome, or non-alcoholic fatty liver disease (NAFLD). Although there is consistent evidence for the positive effects of physical activity on several health aspects, most adolescents in Colombia are sedentary. It is, therefore, important to implement strategies that generate changes in lifestyle. The HEPAFIT study aims to examine whether a 6-month exercise program has benefits for hepatic fat content and cardiovascular health outcomes among overweight/obese adolescents from Bogotá, Colombia. Methods/design: Altogether, 100 hundred overweight/obese, sedentary adolescents (aged 11-17 years) attending two public schools in Bogotá, Colombia, will be included in a parallel-group randomized controlled trial. Adolescents will be randomly assigned to an intervention group following one of four curricula: (1) the standard physical education curriculum (60 min per week of physical activity, n = 25) at low-to-moderate intensity; (2) a high-intensity physical education curriculum (HIPE, n = 25), consisting of endurance and resistance games and non-competitive activities, such as running, gymkhanas, lifting, pushing, wrestling, or hauling, for 60-min sessions, three times per week, with an energy expenditure goal of 300 to 500 kcal/session at 75-85% maximum heart rate (HRmax); (3) a low-to-moderate intensity physical education curriculum (LIPE, n = 25) consisting of endurance and resistance games and non-competitive activities (e.g., chasing, sprinting, dribbling, or hopping) for 60-min sessions, three times per week with an energy expenditure goal of 300 kcal/session at 55-75% HRmax; and (4) a combined HIPE and LIPE curriculum (n = 25). The HIPE, LIPE, and combined interventions were performed in addition to the standard physical education curriculum. The primary outcome for effectiveness is liver fat content, as measured by the controlled attenuation parameter 1 week after the end of the intervention program. Discussion: The translational focus may be suitable for collecting new information in a school setting on the possible effects of physical activity interventions to reduce liver fat content and to improve metabolic profiles and the cardiometabolic health of overweight/obese adolescents. This may lead to the more efficient use of school physical education resources. © 2018 The Author(s).
dc.language.isoen
dc.publisherBioMed Central Ltd.
dc.subjectExercise
dc.subjectFatty liver
dc.subjectMetabolic syndrome
dc.subjectObesity
dc.subjectOverweight
dc.subjectRisk factor
dc.subjectadolescent
dc.subjectadolescent obesity
dc.subjectArticle
dc.subjectcardiovascular disease
dc.subjectColombia
dc.subjectcontrolled study
dc.subjectendurance training
dc.subjectenergy expenditure
dc.subjectexercise
dc.subjectfatty liver
dc.subjecthuman
dc.subjectlifting effort
dc.subjectliver metabolism
dc.subjectparallel design
dc.subjectphysical activity
dc.subjectphysical education
dc.subjectrandomized controlled trial
dc.subjectrandomized controlled trial (topic)
dc.subjectresistance training
dc.subjectrunning
dc.subjectsingle blind procedure
dc.subjectwrestling
dc.subjectadipose tissue
dc.subjectage
dc.subjectblood
dc.subjectbody weight loss
dc.subjectchild
dc.subjectchildhood obesity
dc.subjecthealth status
dc.subjecthealthy lifestyle
dc.subjectliver
dc.subjectmetabolism
dc.subjectobesity
dc.subjectpathophysiology
dc.subjectprocedures
dc.subjectschool health service
dc.subjecttime factor
dc.subjecttreatment outcome
dc.subjectbiological marker
dc.subjectAdipose Tissue
dc.subjectAdiposity
dc.subjectAdolescent
dc.subjectAge Factors
dc.subjectBiomarkers
dc.subjectChild
dc.subjectColombia
dc.subjectExercise
dc.subjectHealth Status
dc.subjectHealthy Lifestyle
dc.subjectHumans
dc.subjectLiver
dc.subjectPediatric Obesity
dc.subjectPhysical Education and Training
dc.subjectRandomized Controlled Trials as Topic
dc.subjectSchool Health Services
dc.subjectSingle-Blind Method
dc.subjectTime Factors
dc.subjectTreatment Outcome
dc.subjectWeight Loss
dc.titleEffects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trial
dc.typeArticle


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