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dc.contributor.authorGarcía-Hermoso A.
dc.contributor.authorCavero-Redondo I.
dc.contributor.authorRamírez-Vélez R.
dc.contributor.authorRuiz J.R.
dc.contributor.authorOrtega F.B.
dc.contributor.authorLee D.-C.
dc.contributor.authorMartínez-Vizcaíno V.
dc.date.accessioned2020-09-02T22:18:47Z
dc.date.available2020-09-02T22:18:47Z
dc.date.issued2018
dc.identifier10.1016/j.apmr.2018.01.008
dc.identifier.citation99, 10, 2100-2113.e5
dc.identifier.issn00039993
dc.identifier.urihttps://hdl.handle.net/20.500.12728/4622
dc.descriptionObjectives: The aims of the present systematic review and meta-analysis were to determine the relationship between muscular strength and all-cause mortality risk and to examine the sex-specific impact of muscular strength on all-cause mortality in an apparently healthy population. Data Sources: Two authors systematically searched MEDLINE, EMBASE and SPORTDiscus databases and conducted manual searching of reference lists of selected articles. Study Selection: Eligible cohort studies were those that examined the association of muscular strength with all-cause mortality in an apparently healthy population. The hazard ratio (HR) estimates with 95% confidence interval (CI) were pooled by using random effects meta-analysis models after assessing heterogeneity across studies. Data Extraction: Two authors independently extracted data. Data Synthesis: Thirty-eight studies with 1,907,580 participants were included in the meta-analysis. The included studies had a total of 63,087 deaths. Higher levels of handgrip strength were associated with a reduced risk of all-cause mortality (HR=0.69; 95% CI, 0.64-0.74) compared with lower muscular strength, with a slightly stronger association in women (HR=0.60; 95% CI, 0.51-0.69) than men (HR=0.69; 95% CI, 0.62-0.77) (all P<.001). Also, adults with higher levels of muscular strength, as assessed by knee extension strength test, had a 14% lower risk of death (HR=0.86: 95% CI, 0.80-0.93; P<.001) compared with adults with lower muscular strength. Conclusions: Higher levels of upper- and lower-body muscular strength are associated with a lower risk of mortality in adult population, regardless of age and follow-up period. Muscular strength tests can be easily performed to identify people with lower muscular strength and, consequently, with an increased risk of mortality. © 2018 American Congress of Rehabilitation Medicine
dc.language.isoen
dc.publisherW.B. Saunders
dc.subjectDeath
dc.subjectHand strength
dc.subjectLeg strength
dc.subjectMuscles
dc.subjectadult
dc.subjectall cause mortality
dc.subjectarticle
dc.subjectcohort analysis
dc.subjectcontrolled study
dc.subjectdata extraction
dc.subjectdata synthesis
dc.subjectdeath
dc.subjectEmbase
dc.subjectfemale
dc.subjectfollow up
dc.subjectgrip strength
dc.subjecthazard ratio
dc.subjecthuman
dc.subjectknee
dc.subjectmale
dc.subjectMedline
dc.subjectmeta analysis
dc.subjectmortality risk
dc.subjectmuscle strength
dc.subjectrisk assessment
dc.subjectsystematic review
dc.subjectaged
dc.subjectcause of death
dc.subjecthealth survey
dc.subjectmiddle aged
dc.subjectmortality
dc.subjectmuscle disease
dc.subjectmuscle strength
dc.subjectpathophysiology
dc.subjectphysiology
dc.subjectproportional hazards model
dc.subjectsex ratio
dc.subjectAdult
dc.subjectAged
dc.subjectCause of Death
dc.subjectCohort Studies
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectMuscle Strength
dc.subjectMuscular Diseases
dc.subjectPopulation Surveillance
dc.subjectProportional Hazards Models
dc.subjectSex Distribution
dc.titleMuscular Strength as a Predictor of All-Cause Mortality in an Apparently Healthy Population: A Systematic Review and Meta-Analysis of Data From Approximately 2 Million Men and Women
dc.typeReview


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