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dc.contributor.authorFuentes-Barros G.
dc.contributor.authorCastro-Saavedra S.
dc.contributor.authorLiberona L.
dc.contributor.authorAcevedo-Fuentes W.
dc.contributor.authorTirapegui C.
dc.contributor.authorMattar C.
dc.contributor.authorCassels B.K.
dc.date.accessioned2020-09-02T22:18:03Z
dc.date.available2020-09-02T22:18:03Z
dc.date.issued2018
dc.identifier10.1016/j.fitote.2018.02.020
dc.identifier.citation127, , 179-185
dc.identifier.issn0367326X
dc.identifier.urihttps://hdl.handle.net/20.500.12728/4542
dc.descriptionEighteen alkaloids were detected in the bark, leaves, wood and roots of Peumus boldus, including traces of secoboldine, N-methylsecoboldine (boldine methine), glaucine and norreticuline, not reported previously as constituents of this species. Using appropriate standards, we quantified thirteen of them by UHPLC-MS/MS. Boldine was dominant in the bark, and laurolitsine in wood and roots. The alkaloid composition of the leaves, determined for 130 individually identified trees, classified by age and sex, was highly variable, where N-methyllaurotetanine, laurotetanine, coclaurine and in some cases isocorydine predominated, but not boldine. © 2018 Elsevier B.V.
dc.language.isoen
dc.publisherElsevier B.V.
dc.subjectAlkaloids
dc.subjectHerbal products
dc.subjectPeumus boldus
dc.subjectPhytochemistry
dc.subjectTraditional medicine
dc.subjectUHPLC-MS/MS
dc.subject6a,7 dehydroboldine
dc.subjectalkaloid derivative
dc.subjectboldine
dc.subjectcoclaurine
dc.subjectglaucine
dc.subjectglaziovine
dc.subjecthigenamine
dc.subjectisoboldine
dc.subjectisocorydine
dc.subjectisocorydine n oxide
dc.subjectlaurolitsine
dc.subjectlaurotetanine
dc.subjectn methylcoclaurine
dc.subjectn methyllaurotetanine
dc.subjectn methylsecoboldine
dc.subjectnorglaucine
dc.subjectnorisocorydine
dc.subjectnorreticuline
dc.subjectpallidine
dc.subjectpeumus boldus extract
dc.subjectplant extract
dc.subjectpronuciferine
dc.subjectreticuline
dc.subjectsecoboldine
dc.subjectsinoacutine
dc.subjectunclassified drug
dc.subjectalkaloid
dc.subjectaporphine derivative
dc.subjectboldine
dc.subjectglaucine
dc.subjectisocorydine
dc.subjectisoquinoline derivative
dc.subjectlaurolitsine
dc.subjectlaurotetanine
dc.subjectnorreticuline
dc.subjectplant extract
dc.subjectArticle
dc.subjectbark
dc.subjectdrug determination
dc.subjectdrug identification
dc.subjectlimit of detection
dc.subjectlimit of quantitation
dc.subjectPeumus boldus
dc.subjectphytochemistry
dc.subjectplant leaf
dc.subjectplant root
dc.subjectpriority journal
dc.subjecttraditional medicine
dc.subjectultra performance liquid chromatography
dc.subjectwood
dc.subjectchemistry
dc.subjecthigh performance liquid chromatography
dc.subjectPeumus boldus
dc.subjecttandem mass spectrometry
dc.subjectAlkaloids
dc.subjectAporphines
dc.subjectChromatography, High Pressure Liquid
dc.subjectIsoquinolines
dc.subjectPeumus
dc.subjectPlant Bark
dc.subjectPlant Extracts
dc.subjectPlant Leaves
dc.subjectPlant Roots
dc.subjectTandem Mass Spectrometry
dc.subjectWood
dc.titleVariation of the alkaloid content of Peumus boldus (boldo)
dc.typeArticle


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