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dc.contributor.authorBersezio C.
dc.contributor.authorSánchez F.
dc.contributor.authorEstay J.
dc.contributor.authorLedezma P.
dc.contributor.authorVernal R.
dc.contributor.authorGarlet G.
dc.contributor.authorOliveira O.B.
dc.contributor.authorFernández E.
dc.date.accessioned2020-09-02T22:13:09Z
dc.date.available2020-09-02T22:13:09Z
dc.date.issued2020
dc.identifier10.1111/jerd.12557
dc.identifier.citation32, 1, 119-126
dc.identifier.issn14964155
dc.identifier.urihttps://hdl.handle.net/20.500.12728/3753
dc.descriptionObjective: This study assessed IL-1β and RANK-L levels in vivo and color stability of non-vital teeth bleached using hydrogen (35%) and carbamide (37%) peroxides 3 months after treatment. Materials and Methods: Fifty teeth were randomly divided into two groups(n = 25):35% hydrogen peroxide (HP) or 37% carbamide peroxide (CP). Four sessions of intracoronal walking-bleach procedure were performed. IL-1β and RANK-L levels were assessed from gingival crevicular fluid samples (from three vestibular and three palatines sites) at eight different time-points: at the beginning of the study (baseline), after four sessions of intracanal bleaching, and at 1 week, 1 month, and 3 months posttreatment. The color variations were visually detected using Vita bleach shade guide (ΔSGU). Results: Significant increases of IL-1β and RANK-L levels were detected at all time-points (all P <.05) when comparing each time-point to baseline, and a high correlation (>0.8—Spearman) between variables. According the ΔSGU values, a color change of five for HP and four for CP were detected. Conclusions: Non-vital walking bleach technique promotes an increase in IL-1β and RANKL levels in periodontal tissues and also, it is maintained until the third-month posttreatment. Clinical Significance: The internal whitening of teeth increases the levels of cytokines associated with inflammation and bone resorption 3 months after the whitening procedure is finished; this should warn of possible harmful effects of this whitening technique. © 2019 Wiley Periodicals, Inc.
dc.language.isoen
dc.publisherBlackwell Publishing Ltd
dc.subjectbiomarkers
dc.subjectdouble-blind study
dc.subjecthydrogen peroxide
dc.subjectRANK-L
dc.subjecttooth bleaching
dc.subjecthydrogen peroxide
dc.subjectperoxide
dc.subjecttooth bleaching agent
dc.subjecturea
dc.subjectcolor
dc.subjectdental procedure
dc.subjectfollow up
dc.subjecthuman
dc.subjecttooth discoloration
dc.subjectColor
dc.subjectFollow-Up Studies
dc.subjectHumans
dc.subjectHydrogen Peroxide
dc.subjectPeroxides
dc.subjectTooth Bleaching
dc.subjectTooth Bleaching Agents
dc.subjectTooth Discoloration
dc.subjectUrea
dc.titleInflammatory markers IL-1β and RANK-L assessment after non-vital bleaching: A 3-month follow-up
dc.typeArticle


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