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dc.contributor.authorArboleya S.
dc.contributor.authorMartinez-Camblor P.
dc.contributor.authorSolís G.
dc.contributor.authorSuárez M.
dc.contributor.authorFernández N.
dc.contributor.authorde los Reyes-Gavilán C.G.
dc.contributor.authorGueimonde M.
dc.date.accessioned2020-09-02T22:12:25Z
dc.date.available2020-09-02T22:12:25Z
dc.date.issued2017
dc.identifier10.3389/fmicb.2017.00183
dc.identifier.citation8, FEB, -
dc.identifier.issn1664302X
dc.identifier.urihttps://hdl.handle.net/20.500.12728/3598
dc.descriptionThe involvement of the gut microbiota on weight-gain and its relationship with childhood undernutrition and growth has been reported. Thus, the gut microbiota constitutes a potential therapeutic target for preventing growth impairment. However, our knowledge in this area is limited. In this study we aimed at evaluating the relationship among early microbiota, growth, and development in preterm infants. To this end we assessed the levels of specific microorganisms by qPCR, and those of short chain fatty acids by mean of gas-chromatography, in feces from 63 preterm newborns and determined their weight-gain during the first months. The statistical analyses performed indicate an influence of the intestinal microbiota in weight-gain, with the levels of some microorganisms showing a significant association with the weight-gain of the infant. The levels of specific microbial groups during the first days of life were found to affect weight gain by the age of 1 month. Moreover, clustering of the infants on the basis of the microbiota composition at 1 month of age rendered groups which showed differences in weight z-scores. Our results suggest an association between the gut microbiota composition and weight-gain in preterm infants at early life and point out potential microbial targets for favoring growth and maturation in these infants. © 2017 Arboleya, Martinez-Camblor, Solís, Suárez, Fernández, de los Reyes-Gavilán and Gueimonde.
dc.language.isoen
dc.publisherFrontiers Research Foundation
dc.subjectColonization
dc.subjectMicrobiota
dc.subjectNewborn
dc.subjectPremature-infant
dc.subjectProbiotics
dc.subjectWeight-gain
dc.subjectshort chain fatty acid
dc.subjectArticle
dc.subjectBacteroides
dc.subjectBifidobacterium
dc.subjectbirth weight
dc.subjectbreast milk
dc.subjectcontrolled study
dc.subjectEnterobacteriaceae
dc.subjectEnterococcus
dc.subjectfeces analysis
dc.subjectfemale
dc.subjectgas chromatography
dc.subjectgestational age
dc.subjecthuman
dc.subjectinfant
dc.subjectintestine flora
dc.subjectLactobacillus
dc.subjectmale
dc.subjectmalnutrition
dc.subjectnonhuman
dc.subjectpolymerase chain reaction
dc.subjectprematurity
dc.subjectscoring system
dc.subjectStaphylococcus
dc.subjectStreptococcus
dc.subjectweight gain
dc.subjectWeissella
dc.titleIntestinal microbiota and weight-gain in preterm neonates
dc.typeArticle


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