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dc.contributor.authorFernández-Rodríguez, Rubén
dc.contributor.authorMonedero-Carrasco, Sonia
dc.contributor.authorBizzozero-Peroni, Bruno
dc.contributor.authorGarrido-Miguel, Miriam
dc.contributor.authorMesas, Arthur Eumann
dc.contributor.authorMartínez-Vizcaíno, Vicente
dc.date.accessioned2024-04-10T03:24:14Z
dc.date.available2024-04-10T03:24:14Z
dc.date.issued2023
dc.identifier10.4093/dmj.2022.0007
dc.identifier.issn22336079
dc.identifier.urihttps://hdl.handle.net/20.500.12728/10773
dc.description.abstractBackground: Type 2 diabetes mellitus (T2DM) is related to increased inflammatory processes. The effects of resistance exercise on inflammatory biomarkers in T2DM are controversial. Our purpose was to determine the effectiveness of resistance exercise on inflammatory biomarkers in patients diagnosed with T2DM. Methods: We searched four databases until September 2021. We included randomized clinical trials (RCTs) of the effects of resistance exercise on inflammatory biomarkers (C-reactive protein [CRP], tumor necrosis factor alpha, interleukin-6, and interleukin-10) in patients with T2DM. A random effects meta-analysis was conducted to determine the standardized mean difference (SMD) and the raw mean difference (MD) for CRP. Results: Thirteen RCTs were included in the review, and 11 in the meta-analysis for CRP. Lower CRP levels were observed when resistance exercise was compared with the control groups (SMD=-0.20; 95% confidence interval [CI], -0.37 to -0.02). When conducting the MD meta-analysis, resistance exercise showed a significant decrease in CRP of -0.59 mg/dL (95% CI, -0.88 to -0.30); otherwise, in the control groups, the CRP values increased 0.19 mg/dL (95% CI, 0.17 to 0.21). Conclusion: Evidence supports resistance exercise as an effective strategy to manage systemic inflammation by decreasing CRP levels in patients with T2DM. The evidence is still inconclusive for other inflammatory biomarkers. Copyright © 2023 Korean Diabetes Association.es_ES
dc.description.sponsorshipMinisterio de Educación, Cultura y Deporte, MECD; European Social Fund, ESF, (2020-PREDU-CLM-16746, BEAGAL18/00093); Universidad de Castilla-La Mancha, UCLM; European Regional Development Fund, ERDFes_ES
dc.language.isoenes_ES
dc.publisherKorean Diabetes Associationes_ES
dc.subjectDiabetes mellituses_ES
dc.subjectExercisees_ES
dc.subjectInflammationes_ES
dc.subjectResistance traininges_ES
dc.titleEffectiveness of Resistance Exercise on Inflammatory Biomarkers in Patients with Type 2 Diabetes Mellitus: A Systematic Review with Meta-Analysises_ES
dc.typeArticlees_ES


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