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dc.contributor.authorPavón, Alequis
dc.contributor.authorCorsini, Gino
dc.contributor.authorOrellana, Paz
dc.contributor.authorCalisto, Nancy
dc.contributor.authorNavarro, Laura
dc.contributor.authorWiese, Guillermo
dc.contributor.authorCortés-Cortés, Piedad
dc.contributor.authorGidekel, Manuel
dc.contributor.authorGutierrez-Moraga, Ana
dc.contributor.authorSalazar, Lorena
dc.date.accessioned2024-04-10T01:54:17Z
dc.date.available2024-04-10T01:54:17Z
dc.date.issued2023
dc.identifier10.4067/S0717-95022023000100286
dc.identifier.issn07179367
dc.identifier.urihttps://hdl.handle.net/20.500.12728/10713
dc.description.abstractCancer is the second leading cause of death in the world and colorectal cancer is the only cancer that has shown a sustained increase in mortality in the last decade. In the search for new chemotherapeutic agents against cancer, extremophilic microorganisms have shown to be a potential source to obtain molecules of natural origin and with selective cytotoxic action towards cancer cells. In this work we analyzed the ability of a collection of Antarctic soil bacteria, isolated on Collins Glacier from the rhizosphere of Deschampsia antarctica Desv plant, to secrete molecules capable of inhibiting cell proliferation of a colorectal cancer tumor line. Our results demonstrated that culture supernatants from the Antarctic bacteria K2I17 and MI12 decreased the viability of LoVo cells, a colorectal adenocarcinoma cell line. Phenotypic and genotypic characterization of the Antarctic bacteria showed that they were taxonomically related and nucleotide identity analysis based on the 16S rRNA gene sequence identified the bacterium K2I17 as a species belonging to the genus Bacillus. © 2023, Universidad de la Frontera. All rights reserved.es_ES
dc.description.sponsorshipUniversidad Autónoma de Coahuila, UAdeCes_ES
dc.language.isoenes_ES
dc.publisherUniversidad de la Fronteraes_ES
dc.subjectAntarctic bacteriaes_ES
dc.subjectAntiproliferative activityes_ES
dc.subjectColorectal canceres_ES
dc.titleIdentification of Antarctic Soil Bacteria Exhibiting Antiproliferative Activity Against a Colon Cancer Cell Linees_ES
dc.title.alternativeIdentificación de Bacterias de Suelo Antártico que Presentan Actividad Antiproliferativa Sobre una Línea Celular de Cáncer de Colones_ES
dc.typeArticlees_ES


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