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dc.contributor.authorGutiérrez, Mario F.
dc.contributor.authorÑaupari-Villasante, Romina
dc.contributor.authorBedoya-Ocampo, Jessica
dc.contributor.authorNuñez, Alejandra
dc.contributor.authorFernández, Eduardo
dc.contributor.authorLoguercio, Alessandro D.
dc.date.accessioned2023-02-20T15:28:20Z
dc.date.available2023-02-20T15:28:20Z
dc.date.issued2023
dc.identifier10.1080/01694243.2023.2166387
dc.identifier.issn01694243
dc.identifier.urihttps://hdl.handle.net/20.500.12728/10195
dc.description.abstractThe aim of this study was to evaluate the anti-MMP activity of two concentrations of copper nanoparticles (CuNp) and the effect of their addition to a universal adhesive system on resin cement-radicular dentin in situ degree of conversion (DC), elastic modulus (EM), nanoleakage (NL), and push-out bond strength (PBS). Anti-MMP activity was evaluated for several MMPs. Seventy-two roots of endodontically prepared human lower premolars were randomly divided into six groups according to CuNp concentration (0% [control], 0.1%, 0.2%) and adhesive strategy (etch-and-rinse [ER] and self-etch [SE]). Fiber posts were cemented, DC was measured using micro-Raman spectroscopy, the EM of the hybrid layer and adhesive layer was measured using a nano-indenter, the NL was evaluated by scanning electron microscopy, and PBS was tested at 0.5 mm/min. Data were analyzed by two-way ANOVA and Tukey’s test (α = 0.05). CuNp demonstrated anti-MMP activity (p < 0.01). CuNp containing-adhesives showed significant increased DC (p = 0.01), increased EM in the hybrid layer and adhesive layer (p = 0.001), decreased NL values (p = 0.001), and increased PBS (p = 0.0001). Adhesive strategy was not statistically significant (p > 0.47). Usually, a significant difference among root thirds was observed, except for DC and NL when CuNp 0.2% was evaluated. This is the first in vitro study showing that the incorporation of CuNp in an adhesive is an achievable alternative that can provide anti-MMP activity and improve the mechanical and bonding properties to root canal dentin.es_ES
dc.language.isoenes_ES
dc.publisherTaylor and Francis Ltd.es_ES
dc.subjectcopperes_ES
dc.subjectmetalloproteinaseses_ES
dc.subjectnanoleakagees_ES
dc.subjectnanoparticleses_ES
dc.subjectpush-out bond strengthes_ES
dc.subjectUniversal adhesive systemes_ES
dc.titleA universal adhesive containing copper nanoparticles improves the bonding and mechanical properties of resin cement–root dentin interface: an in vitro studyes_ES
dc.typeArticlees_ES


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