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Synthesis and Docking of Novel 3-Indolylpropyl Derivatives as New Polypharmacological Agents Displaying Affinity for 5-HT1AR/SERT
5-Hydroxytryptamine 1...
Docking
Indole
Piperazinylpropylindo...
Serotonin transporter...
1 benzyl 3 [[4 [3 (1h...
1 benzyl 3 [[4 [3 (5 ...
1 benzyl 3 [[4 [3 (5 ...
1 benzyl 3 [[4 [3 (5 ...
1 [3 (1h indol 3 yl)p...
2 dipropylamino 8 hyd...
4 [4 [3 (1h indol 3 y...
4 [4 [3 (1h indol 3 y...
4 [4 [3 (1h indol 3 y...
6 methoxy 1 [3 (5 met...
fluoxetine
indole derivative
n [(1 benzyl 5 fluoro...
propane
serotonin 1A agonist
serotonin 1A receptor...
serotonin transporter...
serotonin uptake inhi...
unclassified drug
[3 (5 bromo 1h indol ...
[3 (5 fluoro 1h indol...
antidepressant agent
indole derivative
serotonin 1A receptor...
serotonin receptor af...
serotonin transporter...
Article
binding affinity
biological activity
competitive binding a...
controlled study
crystal structure
drug binding
drug potency
drug screening
drug selectivity
drug synthesis
human
molecular docking
molecular dynamics
polypharmacology
priority journal
substitution reaction...
chemical structure
chemistry
dose response
metabolism
structure activity re...
synthesis
Antidepressive Agents...
Dose-Response Relatio...
Humans
Indoles
Molecular Docking Sim...
Molecular Structure
Receptor, Serotonin, ...
Serotonin Agents
Serotonin Plasma Memb...
Structure-Activity Re...