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Synthesis of Novel Lipoic Acid Derivates

2024, González Gutiérrez, Juan Pablo, Moris, S., Barrientos, C.

Lipoic acid is a naturally occurring compound involved in biological processes with special reactivity due to its 1,2-dithiolane ring. The novel ALA derivatives were synthesized using the Steglich esterification in mild conditions and then concentrated and neutralized with yields of 45.1 to 81.2%.