Comparative effect of antihypertensive drugs in improving arterial stiffness in hypertensive adults (RIGIPREV study). a protocol for network meta-analysis
Autor
Cavero-Redondo, Iván
Saz-Lara, Alicia
García-Ortíz, Luís H.
Lugones-Sánchez, Cristina
Notario-Pacheco, Blanca
Gómez-Sánchez, Leticia
Martinez Vizcaino, Vicente J.
Gómez-Marcos, Manuel Ángel
Resumen
(1) Background: Arterial stiffness is closely and bi-directionally related to hypertension and is understood as both a cause and a consequence of hypertension. Several studies suggest that antihypertensive drugs may reduce arterial stiffness. Therefore, effective prescription of antihyper-tensive drugs should consider both blood pressure and arterial stiffness. The aim of this protocol is to provide a review comparing the effects of different types of antihypertensive drug interventions on the reduction of arterial stiffness in hypertensive subjects. (2) Methods: The literature search will be performed through the MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and Web of Science databases. Randomised clinical trials assessing the effect of antihypertensive drug interventions on arterial stiffness measured in subjects with hypertension will be included. A frequentist network meta-analysis will be performed to determine the comparative effects of different antihypertensive drugs. (3) Results: The findings of this study will be published in a peer-reviewed journal. (4) Conclusions: This study will provide evidence for health care professionals on the efficacy of different antihypertensive drugs in decreasing arterial stiffness; in addition, it will analyse the efficacy of the drugs not only in terms of arterial stiffness but also in terms of blood pressure treatment.
Colecciones
Ítems relacionados
Mostrando ítems relacionados por Título, autor o materia.
-
Article
Comparative effect of antihypertensive drugs in improving arterial stiffness in adults with hypertension (RIGIPREV study). A network meta-analysis (2024)
Cavero-Redondo, Iván; Saz-Lara, Alicia; Lugones-Sánchez, Cristina; Pozuelo-Carrascosa, Diana P.; Gómez-Sánchez, Leticia; López-Gil, José Francisco; García-Ortiz, Luis; Bruno, Rosa Maria; Gómez-Marcos, Manuel Ángel (Frontiers Media SA, 2023)Aims: To synthesize and evaluate the available scientific evidence on the efficacy of antihypertensive drugs on arterial stiffness in patients with hypertension by using a network meta-analysis approach. Methods: A systematic ... -
Article
The Comparative Effects of Different Types of Oral Vitamin Supplements on Arterial Stiffness: A Network Meta-Analysis (2022)
Saz-Lara, Alicia; Cavero-Redondo, Iván; Martinez Vizcaino, Vicente J.; Martínez-Ortega, Isabel Antonia; Notario-Pacheco, Blanca; Pascual-Morena, Carlos (MDPI, 2022-03-01)Arterial stiffness, a significant prognostic factor of cardiovascular disease, may be affected by dietary factors. Research on the effects of oral vitamin supplements on arterial stiffness and/or endothelial function has ... -
Article
Association Between Arterial Stiffness and Blood Pressure Progression With Incident Hypertension: A Systematic Review and Meta-Analysis (2024)
Saz-Lara, Alicia; Bruno, Rosa María; Cavero-Redondo, Iván; Álvarez-Bueno, Celia; Notario-Pacheco, Blanca; Martínez-Vizcaíno, Vicente (Frontiers Media S.A., 2022)Background: Arterial stiffness is an independent predictor of cardiovascular and all-cause mortality that is classically regarded as a consequence of arterial hypertension. However, a growing number of studies have shown ...