Role for physical fitness in the association between age and cognitive function in older adults: A mediation analysis of the SABE colombia study
Autor
Pérez-Sousa, Miguel Ángel
Del Pozo-Cruz, Jesús
Olivares, Pedro R.
Cano-Gutierrez, Carlos
Izquierdo, Mikel
Ramírez-Vélez, Robinson
Resumen
Objectives. We investigated the association between physical fitness and cognitive status. Further, we examined whether physical fitness mediates the association between cognitive functioning and aging. Design. Cross-sectional study. Setting. Urban and rural Colombian older adults. Methods. 4416 participants from the SABE study were included in the current analysis. Physical fitness was assessed with the handgrip test and the usual gait speed test. Cognitive status was evaluated through the Folstein Mini-Mental State Examination. A parallel mediation path was used to test the possible mediator role of physical fitness between aging and cognitive functioning. Results. Older adults with lower handgrip strength (HGS) were more likely to have mild-cognitive status than older adults with healthy HGS (OR = 1.53, 95% CI = 1.15; 2.02). In addition, older adults with a slower gait speed were more likely to have mild cognitive impairment (OR = 2.05, 95% CI = 1.54; 2.78). Age had an inverse relationship with cognitive function (β = -0.110, 95% CI = -0.130; -0.100) and it was also inversely associated with HGS (β = -0.003, 95% CI = -0.005; -0.002) and gait speed (β = -0.010, 95% CI = -0.011; -0.009). The indirect effects, which indicate that the effect of age on cognitive function is transmitted through mediators, showed that both gait speed (β = -0.028, 95% CI = -0.036; -0.020) and HGS (β = -0.014, 95% CI = -0.024; -0.005) were independent mediators of the detrimental effect of aging on cognitive function. Conclusions. Physical fitness mediates the effects of aging on cognitive functioning. Our findings suggest that physical activity can be a key factor to prevent cognitive deterioration during aging process.
Colecciones
Ítems relacionados
Mostrando ítems relacionados por Título, autor o materia.
-
Article
Can physical activity attenuate the negative association between sitting time and cognitive function among older adults? A mediation analysis (2020)
García-Hermoso A.; Ramírez-Vélez R.; Celis-Morales C.A.; Olloquequi J.; Izquierdo M. (Elsevier Inc., 2018) -
Article
Comparison of the Psychometric Properties of the EQ-5D-3L-Y and EQ-5D-5L-Y Instruments in Spanish Children and Adolescents (2021)
Pérez-Sousa, Miguel Ángel; Olivares, Pedro R.; Ramírez-Vélez, Robinson; Gusi, Narcís (Elsevier Ltd, 2021)Objectives: The study aimed to assess the reliability and validity of EQ-5D-5L-Y and to compare the performance of EQ-5D-5L-Y with EQ-5D-3L-Y in children and adolescents. Methods: The Spanish versions of the 3L and 5L of ... -
Article
Association between exercise-induced changes in cardiorespiratory fitness and adiposity among overweight and obese youth: A meta-analysis and meta-regression analysis (2021)
García-Hermoso, Antonio; Izquierdo, Mikel; Alonso-Martinez, Alicia M.; Faigenbaum, Avery D.; Olloquequi, Jordi; Ramírez-Vélez, Robinson (MDPI, 2020-09)The aim of this study was to determine the minimum change in cardiorespiratory fitness (CRF) required to reduce adiposity (percent body fat) in exercise programs for overweight and obese youth. Studies were identified ...