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Are advanced glycation end products in skin associated with vascular dysfunction markers? A meta-analysis
dc.contributor.author | Saz-Lara, Alicia | |
dc.contributor.author | Álvarez-Bueno, Celia | |
dc.contributor.author | Solera-Martínez, Montserrat | |
dc.contributor.author | Notario-Pacheco, Blanca | |
dc.contributor.author | Sequí-Dominguez, Irene | |
dc.contributor.author | Cavero-Redondo, Iván | |
dc.date.accessioned | 2020-09-28T14:47:59Z | |
dc.date.available | 2020-09-28T14:47:59Z | |
dc.date.issued | 2020-09-02 | |
dc.identifier | 10.3390/ijerph17186936 | |
dc.identifier.issn | 16617827 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12728/6915 | |
dc.description.abstract | Evidence exists regarding the association between advanced glycation end products and different cardiovascular disease subclinical processes, such as arterial stiffness and atherosclerosis. With this systematic review and meta-analysis, we aimed to provide a synthesis of the evidence regarding the association of arterial stiffness measured by pulse wave velocity and atherosclerosis measured by carotid intima media thickness with skin autofluorescence. A systematic search was performed using: MEDLINE (PubMed), SCOPUS, and Web of Science, until 30 March 2020. Cross-sectional studies or baseline data from prospective longitudinal studies were considered. The DerSimonian and Laird method was used to calculate the pooled estimates of correlation coefficients and the corresponding 95% confidence intervals (CI) for the association of pulse wave velocity and carotid intima media thickness with skin autofluorescence. Twenty-five studies were included in the systematic review and meta-analysis, including 6306 subjects. The pooled correlation coefficient was 0.25 (95% CI: 0.18, 0.31) for pulse wave velocity and skin autofluorescence, and 0.31 (95% CI: 0.25, 0.38) for carotid intima media thickness and skin autofluorescence. This systematic review and meta-analysis provide a synthesis of the evidence showing a positive weak association of pulse wave velocity and carotid intima media thickness with skin autofluorescence. | es_ES |
dc.language.iso | en | es_ES |
dc.publisher | MDPI AG | es_ES |
dc.subject | Advanced glycation end products | es_ES |
dc.subject | Arterial stiffness | es_ES |
dc.subject | Cardiovascular disease | es_ES |
dc.subject | Carotid intima media thickness | es_ES |
dc.subject | Pulse wave velocity | es_ES |
dc.subject | Skin autofluorescence | es_ES |
dc.title | Are advanced glycation end products in skin associated with vascular dysfunction markers? A meta-analysis | es_ES |
dc.type | Article | es_ES |