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dc.contributor.authorÁlvarez-Bueno C.
dc.contributor.authorCavero-Redondo I.
dc.contributor.authorLucas-de la Cruz L.
dc.contributor.authorNotario-Pacheco B.
dc.contributor.authorMartínez-Vizcaíno V.
dc.date.accessioned2020-09-02T22:31:05Z
dc.date.available2020-09-02T22:31:05Z
dc.date.issued2017
dc.identifier10.1093/IJE/DYX122
dc.identifier.citation46, 5, 1653-1666
dc.identifier.issn03005771
dc.identifier.urihttps://hdl.handle.net/20.500.12728/6721
dc.descriptionBackground: Obesity and overweight during pregnancy have been negatively associated with fetal and offspring neurodevelopment. The aim of this systematic review and metaanalysis was to assess the effect of the relationship between pre-pregnancy overweight and obesity with children's neurocognitive development. Methods: We systematically searched MEDLINE, EMBASE, the Cochrane Library and the Web of Science databases from their inception through February 2017 for follow-up studies comparing the relationship between pre-pregnancy weight status and children's cognition. The Mantel-Haenszel fixed-effects method was used to calculate pooled effect size (ES) values and their corresponding 95% confidence intervals (CIs) comparing children's neurocognitive development between pre-pregnancy normal weight, as reference, with overweight and obesity categories. Results: Fifteen articles were included in the systematic review, and nine of them in the meta-analysis. The pooled ES values for overweight and obese mothers were -0.02 (95% CI: -0.05 to 0.02) and -0.06 (95% CI: -0.09 to -0.03), respectively. The pooled ES for the relationship between pre-gestational excess weight (overweight and obesity) and children's neurocognitive development was -0.04 (95% CI: -0.06 to -0.02). Conclusions: Pre-pregnancy obesity might have negative consequences on the neurocognitive development of offspring. © The Author 2017; Published by Oxford University Press on behalf of the International Epidemiological Association. All rights reserved.
dc.language.isoen
dc.publisherOxford University Press
dc.subjectChildren
dc.subjectCognition
dc.subjectCognitive function
dc.subjectNeurocognitive development
dc.subjectObesity
dc.subjectPregnancy
dc.subjectchild health
dc.subjectliterature review
dc.subjectmeta-analysis
dc.subjectnervous system disorder
dc.subjectobesity
dc.subjectobservational method
dc.subjectpregnancy
dc.subjectArticle
dc.subjectchild development
dc.subjectCochrane Library
dc.subjectcognitive development
dc.subjectEmbase
dc.subjectfollow up
dc.subjecthuman
dc.subjectmaternal obesity
dc.subjectMedline
dc.subjectmeta analysis
dc.subjectobservational study
dc.subjectpriority journal
dc.subjectsystematic review
dc.subjectWeb of Science
dc.subjectbody mass
dc.subjectchild
dc.subjectchild development
dc.subjectcognition
dc.subjectfemale
dc.subjectmental disease
dc.subjectobesity
dc.subjectpregnancy
dc.subjectpregnancy complication
dc.subjectrisk factor
dc.subjectBody Mass Index
dc.subjectChild
dc.subjectChild Development
dc.subjectCognition
dc.subjectFemale
dc.subjectHumans
dc.subjectNeurodevelopmental Disorders
dc.subjectObesity
dc.subjectObservational Studies as Topic
dc.subjectOverweight
dc.subjectPregnancy
dc.subjectPregnancy Complications
dc.subjectRisk Factors
dc.titleAssociation between pre-pregnancy overweight and obesity and children's neurocognitive development: A systematic review and meta-analysis of observational studies
dc.typeArticle


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