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Histopathological analysis of unilateral condylar hyperplasia: difficulties in diagnosis and characterization of the disease

dc.contributor.authorVásquez B.
dc.contributor.authorOlate S.
dc.contributor.authorCantín M.
dc.contributor.authorSandoval C.
dc.contributor.authorFariña R.
dc.contributor.authordel Sol M.
dc.date.accessioned2020-09-02T22:30:28Z
dc.date.available2020-09-02T22:30:28Z
dc.date.issued2016
dc.identifier10.1016/j.ijom.2015.11.023
dc.identifier.citation45, 5, 601-609
dc.identifier.issn09015027
dc.identifier.urihttps://hdl.handle.net/20.500.12728/6600
dc.descriptionThe aim of this study was to perform a histological analysis of the conditions in patients undergoing surgery for unilateral condylar hyperplasia (UCH) using different histopathological analytical techniques and to describe the complications and existing controversy in order to better define the disease. A partial condylectomy was performed in five patients who had been diagnosed with UCH using clinical and imaging methods. The samples obtained were analyzed using routine histological techniques including haematoxylin–eosin, Van Gieson, picrosirius, alcian blue/haematoxylin–eosin, and AgNOR staining. The analyses were performed by an observer who was blinded to the clinical parameters of the disease. The cellularity, tissue layers, size of the anatomical structures, and the relationships between them were assessed. The analysis of these patients was complemented by a review of the scientific literature. Variability was observed in the analysis of the cases. The presence of connective tissue was detected at the bone level, with cartilage formation at different levels. Each island presented levels of involvement that could indicate various degrees of aggressiveness. Type I collagen was observed in most cases, although type III was also identified. The development of histological diagnostic methods to determine the aggressiveness or level of involvement in UCH is not currently possible. Further studies are needed to establish new histological classifications. © 2015 International Association of Oral and Maxillofacial Surgeons
dc.language.isoen
dc.publisherChurchill Livingstone
dc.subjectcondylar hyperplasia
dc.subjectcondylectomy
dc.subjectfacial asymmetry
dc.subjectalcian blue
dc.subjectcollagen type 1
dc.subjectcollagen type 3
dc.subjecteosin
dc.subjecthematoxylin
dc.subjectadolescent
dc.subjectadult
dc.subjectArticle
dc.subjectbone plate
dc.subjectcamera
dc.subjectclinical article
dc.subjectcondylectomy
dc.subjectdiagnostic procedure
dc.subjectfemale
dc.subjecthistopathology
dc.subjecthuman
dc.subjecthuman cell
dc.subjecthuman tissue
dc.subjectjaw disease
dc.subjectmale
dc.subjectmandible condyle
dc.subjectmicroscope
dc.subjectmicrotome
dc.subjectoral surgery
dc.subjectpathological anatomy
dc.subjectsilver staining
dc.subjectunilateral condylar hyperplasia
dc.subjectcase report
dc.subjectdiagnostic imaging
dc.subjectface asymmetry
dc.subjecthyperplasia
dc.subjectpathology
dc.subjectsingle photon emission computed tomography
dc.subjectAdolescent
dc.subjectFacial Asymmetry
dc.subjectFemale
dc.subjectHumans
dc.subjectHyperplasia
dc.subjectMale
dc.subjectMandibular Condyle
dc.subjectTomography, Emission-Computed, Single-Photon
dc.titleHistopathological analysis of unilateral condylar hyperplasia: difficulties in diagnosis and characterization of the disease
dc.typeArticle


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