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Effect of different types of exercise on health-related quality of life during and after cancer treatment: a protocol for a systematic review and network meta-analysis

dc.contributor.authorUbago-Guisado E.
dc.contributor.authorGracia-Marco L.
dc.contributor.authorCavero-Redondo I.
dc.contributor.authorMartinez-Vizcaino V.
dc.contributor.authorNotario-Pacheco B.
dc.contributor.authorPozuelo-Carrascosa D.P.
dc.contributor.authorAdalia E.G.
dc.contributor.authorÁlvarez-Bueno C.
dc.date.accessioned2020-09-02T22:29:26Z
dc.date.available2020-09-02T22:29:26Z
dc.date.issued2019
dc.identifier10.1136/bmjopen-2019-031374
dc.identifier.citation9, 11, -
dc.identifier.issn20446055
dc.identifier.urihttps://hdl.handle.net/20.500.12728/6452
dc.descriptionIntroduction Cancer (and survival) is known to affect the quality of life. Strategies as physical activity and exercise during and after cancer may improve health-related qualify of life (HRQOL) outcomes and are, therefore, of clinical and public health importance. To the best of our knowledge, comparative evidence of the effect of the different types of exercise on improving HRQOL in cancer patients has not been synthesised thus far. We aim to conduct a systematic review and network meta-analysis in order to synthesise all available evidence regarding the effect of different types of exercise interventions on HRQOL during and after cancer treatment. Methods and analysis MEDLINE (via PubMed), Web of Science, Embase, The Cochrane Library and SPORTDiscus will be searched from inception to December 2018 for relevant randomised controlled trials (RCTs) and non-RCTs. Studies assessing physical activity and exercise interventions in cancer patients (during treatment) and survivors (after treatment) will be selected. Two independent reviewers will identify eligible studies. After quality appraisal and data extraction, we will conduct meta-analyses for outcomes of interest, including data from mental and physical dimensions of cancer-specific and/or generic HRQOL questionnaires. Risk of bias assessments will be completed using the Quality Assessment Tool for Quantitative Studies. Study heterogeneity will be measured by the I 2 statistic. Bayesian (and traditional approach) network meta-analysis will be performed when possible to determine the comparative effect of the different physical activity or exercise interventions. Ethics and dissemination This systematic review and network meta-analysis will synthesise evidence on the effect of different types of exercise interventions on HRQOL during and after cancer treatment. The results will be disseminated by publication in a peer-reviewed journal and through scientific conferences and symposia. Ethical approval will not be required because the data used for this work will be exclusively extracted from published studies. PROSPERO registration number CRD42019125028. © Author(s) (or their employer(s)) 2019.
dc.language.isoen
dc.publisherBMJ Publishing Group
dc.subjectchemotherapy
dc.subjectoncology
dc.subjectpublic health
dc.subjectradiotherapy
dc.subjectsports medicine
dc.subjectadult
dc.subjectarticle
dc.subjectcancer patient
dc.subjectcancer survival
dc.subjectcancer therapy
dc.subjectchemotherapy
dc.subjectCochrane Library
dc.subjectcontrolled study
dc.subjectdata extraction
dc.subjectEmbase
dc.subjectexercise
dc.subjectfemale
dc.subjecthuman
dc.subjectmale
dc.subjectMedline
dc.subjectmeta analysis
dc.subjectnetwork meta-analysis
dc.subjectphysical activity
dc.subjectpublic health
dc.subjectquality assessment tool
dc.subjectquality of life
dc.subjectquantitative analysis
dc.subjectquestionnaire
dc.subjectradiotherapy
dc.subjectrandomized controlled trial (topic)
dc.subjectrisk assessment
dc.subjectsports medicine
dc.subjectsurvivor
dc.subjectsystematic review
dc.subjectWeb of Science
dc.titleEffect of different types of exercise on health-related quality of life during and after cancer treatment: a protocol for a systematic review and network meta-analysis
dc.typeArticle


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