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Severe acute kidney injury in critically ill children: Epidemiology and prognostic factors [Daño renal agudo grave en niños críticos: epidemiología y factores pronósticos]

dc.contributor.authorTouza Pol P.
dc.contributor.authorRey Galán C.
dc.contributor.authorMedina Villanueva J.A.
dc.contributor.authorMartinez-Camblor P.
dc.contributor.authorLópez-Herce J.
dc.date.accessioned2020-09-02T22:29:22Z
dc.date.available2020-09-02T22:29:22Z
dc.date.issued2015
dc.identifier10.1016/j.anpedi.2015.01.009
dc.identifier.citation83, 6, 367-375
dc.identifier.issn16954033
dc.identifier.urihttps://hdl.handle.net/20.500.12728/6430
dc.descriptionIntroduction Acute kidney injury (AKI) is a severe complication in critically ill children. The aim of the study was to describe the characteristics of AKI, as well as to analyse the prognostic factors for mortality and renal replacement therapy (RRT) in children admitted to Paediatric Intensive Care Units (PICUs) in Spain. Patients and methods Prospective observational multicentre study including children from 7 days to 16 years old who were admitted to a PICU. A univariate and multivariate logistic regression analysis of the risk factors for mortality and renal replacement therapy at PICU discharge were performed. Results A total of 139 cases of AKI were analysed. RRT was necessary in 60.1% of cases. Mortality rate was 32.6%. At PICU discharge RRT was necessary in 15% of survivors. Thrombopenia and low creatinine clearance values were prognostic markers of RRT at PICU discharge. High values of platelets, serum creatinine and weight were associated with higher survival. Conclusions Critically ill children with AKI had a high mortality and morbidity rate. Platelet values and creatinine clearance are markers of RRT at PICU discharge, whereas number of platelets, serum creatinine and weight were associated with mortality. © 2014 Asociación Española de Pediatría
dc.language.isoen
dc.language.isoes
dc.publisherElsevier Doyma
dc.subjectAcute kidney injury
dc.subjectMortality
dc.subjectOutcome
dc.subjectPaediatric Intensive Care Units
dc.subjectRenal replacement therapy
dc.subjectcreatinine
dc.subjectacute kidney failure
dc.subjectadolescent
dc.subjectArticle
dc.subjectchild
dc.subjectcreatinine clearance
dc.subjectcritically ill patient
dc.subjecthospital admission
dc.subjecthospital discharge
dc.subjecthuman
dc.subjectmajor clinical study
dc.subjectmorbidity
dc.subjectmortality rate
dc.subjectmulticenter study
dc.subjectmultivariate logistic regression analysis
dc.subjectobservational study
dc.subjectpediatric intensive care unit
dc.subjectprognosis
dc.subjectprospective study
dc.subjectrenal replacement therapy
dc.subjectrisk factor
dc.subjectSpain
dc.subjectsurvival
dc.subjectthrombocyte count
dc.subjectunivariate analysis
dc.subjectAcute Kidney Injury
dc.subjectclinical trial
dc.subjectcritical illness
dc.subjectinfant
dc.subjectnewborn
dc.subjectpreschool child
dc.subjectAcute Kidney Injury
dc.subjectAdolescent
dc.subjectChild
dc.subjectChild, Preschool
dc.subjectCritical Illness
dc.subjectHumans
dc.subjectInfant
dc.subjectInfant, Newborn
dc.subjectPrognosis
dc.subjectProspective Studies
dc.subjectRenal Replacement Therapy
dc.subjectSpain
dc.titleSevere acute kidney injury in critically ill children: Epidemiology and prognostic factors [Daño renal agudo grave en niños críticos: epidemiología y factores pronósticos]
dc.typeArticle


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