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Lean mass as a total mediator of the influence of muscular fitness on bone health in schoolchildren: a mediation analysis

dc.contributor.authorTorres-Costoso A.
dc.contributor.authorGracia-Marco L.
dc.contributor.authorSánchez-López M.
dc.contributor.authorGarcía-Prieto J.C.
dc.contributor.authorGarcía-Hermoso A.
dc.contributor.authorDíez-Fernández A.
dc.contributor.authorMartínez-Vizcaíno V.
dc.date.accessioned2020-09-02T22:29:19Z
dc.date.available2020-09-02T22:29:19Z
dc.date.issued2015
dc.identifier10.1080/02640414.2014.964750
dc.identifier.citation33, 8, 817-830
dc.identifier.issn02640414
dc.identifier.urihttps://hdl.handle.net/20.500.12728/6414
dc.descriptionAbstract: This report aims to analyse the independent association of lean mass and muscle fitness with bone mineral content (BMC) and bone mineral density (BMD), and to examine whether the relationship between muscle fitness and bone health is mediated by lean mass. Body composition (by dual energy X-ray absorptiometry (DXA)), muscle fitness, physical activity, age and height were measured in 132 schoolchildren (62 boys, aged 8–11 years). Analysis of covariance tested differences in bone-related variables by lean mass and muscle fitness, controlling for different sets of confounders. Linear regression models fitted for mediation analyses examined whether the association between muscle fitness and bone mass was mediated by lean mass. Children with good performance in handgrip and standing long jump had better and worse bone health, respectively. These differences disappeared after controlling for lean mass. Children with high lean mass had higher values in all bone-related variables. In addition, the relationship between muscle fitness and bone mass was fully mediated by lean mass. In conclusion, the relationship between upper-limbs muscle fitness and bone health seems to be dependent on lean mass but not on muscle fitness. Schoolchildren with high lean mass have more BMC and BMD in all regions. Lean mass mediates the association between muscle fitness and bone mass. © 2014, © 2014 Taylor & Francis.
dc.language.isoen
dc.publisherRoutledge
dc.subjectbody composition
dc.subjectbone mineral content
dc.subjectbone mineral density
dc.subjectchildren
dc.subjectmuscular strength
dc.subjectarm
dc.subjectbody composition
dc.subjectbody mass
dc.subjectbone density
dc.subjectchild
dc.subjectcontrolled study
dc.subjectcross-sectional study
dc.subjectexercise test
dc.subjecthuman
dc.subjectleg
dc.subjectmale
dc.subjectmuscle strength
dc.subjectphoton absorptiometry
dc.subjectphysiology
dc.subjectprocedures
dc.subjectrandomized controlled trial
dc.subjectskeletal muscle
dc.subjectAbsorptiometry, Photon
dc.subjectBody Composition
dc.subjectBody Mass Index
dc.subjectBone Density
dc.subjectChild
dc.subjectCross-Sectional Studies
dc.subjectExercise Test
dc.subjectHumans
dc.subjectLower Extremity
dc.subjectMale
dc.subjectMuscle Strength
dc.subjectMuscle, Skeletal
dc.subjectUpper Extremity
dc.titleLean mass as a total mediator of the influence of muscular fitness on bone health in schoolchildren: a mediation analysis
dc.typeArticle


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