Mostrar el registro sencillo del ítem

Whole-genome sequencing analysis of Salmonella enterica serovar enteritidis isolates in chile provides insights into possible transmission between gulls, poultry, and humans

dc.contributor.authorToro M.
dc.contributor.authorRetamal P.
dc.contributor.authorAyers S.
dc.contributor.authorBarreto M.
dc.contributor.authorAllard M.
dc.contributor.authorBrown E.W.
dc.contributor.authorGonzalez-Escalona N.
dc.date.accessioned2020-09-02T22:29:17Z
dc.date.available2020-09-02T22:29:17Z
dc.date.issued2016
dc.identifier10.1128/AEM.01760-16
dc.identifier.citation82, 20, 6223-6232
dc.identifier.issn00992240
dc.identifier.urihttps://hdl.handle.net/20.500.12728/6399
dc.descriptionSalmonella enterica subsp. enterica serotype Enteritidis is a major cause of human salmonellosis worldwide; however, little is known about the genetic relationships between S. Enteritidis clinical strains and S. Enteritidis strains from other sources in Chile. We compared the whole genomes of 30 S. Enteritidis strains isolated from gulls, domestic chicken eggs, and humans in Chile, to investigate their phylogenetic relationships and to establish their relatedness to international strains. Core genome multilocus sequence typing (cgMLST) analysis showed that only 246/4,065 shared loci differed among these Chilean strains, separating them into two clusters (I and II), with cluster II being further divided into five subclusters. One subcluster (subcluster 2) contained strains from all surveyed sources that differed at 1 to 18 loci (of 4,065 loci) with 1 to 18 single-nucleotide polymorphisms (SNPs), suggesting interspecies transmission of S. Enteritidis in Chile. Moreover, clusters were formed by strains that were distant geographically, which could imply that gulls might be spreading the pathogen throughout the country. Our cg- MLST analysis, using other S. Enteritidis genomes available in the National Center for Biotechnology Information (NCBI) database, showed that S. Enteritidis strains from Chile and the United States belonged to different lineages, which suggests that S. Enteritidis regional markers might exist and could be used for trace-back investigations. © 2016, American Society for Microbiology. All Rights Reserved.
dc.language.isoen
dc.publisherAmerican Society for Microbiology
dc.titleWhole-genome sequencing analysis of Salmonella enterica serovar enteritidis isolates in chile provides insights into possible transmission between gulls, poultry, and humans
dc.typeArticle


Ficheros en el ítem

Thumbnail
Nombre:
item_2-s2.0-84991211493.pdf
Tamaño:
2.393Kb
Formato:
PDF
Ver/

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem