Nanomedicine and Parkinson’s disease: A nanoparticle medical approach

Sobarzo-Sánchez E.; Nabavi S.M.; Rastrelli L.; Uriarte E.

dc.contributor.author	Sobarzo-Sánchez E.
dc.contributor.author	Nabavi S.M.
dc.contributor.author	Rastrelli L.
dc.contributor.author	Uriarte E.
dc.date.accessioned	2020-09-02T22:28:44Z
dc.date.available	2020-09-02T22:28:44Z
dc.date.issued	2018
dc.identifier.uri	https://hdl.handle.net/20.500.12728/6326
dc.description	The challenge to obtain new formulations that can give us an effective medical tool to prepare active drugs with low bioavailability to combat Parkinson’s disease, from commercial and natural sources, it has afforded investigations using nanomedicine as basic concept in the scientific research. Supramolecular systems that include carbonnanotubes, natural polymers as chitosan, for instance, and a series of substances whose chemical structure can be modified to encapsulate all type of apolar compounds with low solubility in aqueous system and limited bioavailability in the living system, are exposed as drug delivery system. The success of the nanomedicine to the service of the patients in the early stages of the Parkinson’s disease is due to the low cytotoxicity of the complex drug/carrier, little concentration of the active compound inside the nanocarrier, and finally an easier release of the compound in controlled release depending of the nanostructure of the carrier. Some examples about the formation of nanoparticles from organometallic compounds and its medical application in the treatment of Parkinson’s disease are mentioned and discussed. © 2018 Nova Science Publishers, Inc.
dc.language.iso	en
dc.publisher	Nova Science Publishers, Inc.
dc.subject	Nanomedicine
dc.subject	Nanoparticles
dc.subject	Neurodegenerative diseases
dc.subject	Parkinson’s disease
dc.subject	Protein amyloid aggregation
dc.title	Nanomedicine and Parkinson’s disease: A nanoparticle medical approach
dc.type	Book Chapter