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Multifocal canalicular adenoma of the minor labial salivary glands

dc.contributor.authorSamar M.E.
dc.contributor.authorAvila R.E.
dc.contributor.authorFonseca I.B.
dc.contributor.authorAnderson W.
dc.contributor.authorFonseca G.M.
dc.contributor.authorCantín M.
dc.date.accessioned2020-09-02T22:28:16Z
dc.date.available2020-09-02T22:28:16Z
dc.date.issued2014
dc.identifier.citation7, 11, 8205-8210
dc.identifier.issn19362625
dc.identifier.urihttps://hdl.handle.net/20.500.12728/6259
dc.descriptionCanalicular adenoma (CA) is an uncommon benign neoplasia of salivary glands which is clinically difficult to recognise. Despite having an excellent prognosis, the histological diagnosis and clinical management of this entity can be troublesome. While the main differential diagnosis to consider is basal cell adenoma (BCA), similar histological patterns and multifocality have been observed in adenoid cystic carcinoma (ACC) and polymorphous low-grade adenocarcinoma (PLGA), both locally-aggressive malignancies which require radically different treatment to CA. An emphasis has been placed on the value of immunohistochemistry in avoiding diagnostic and surgical errors. CA is positive for AE1/AE3, CD117 and S-100 protein, and negative for p63, a-SMA, Ki 67 and vimentin. Here we discuss the case of a 61-year-old female with CA in her right upper lip, showing multifocal growth histologically. The differential diagnosis with other adenomas is discussed in addition to the role of immunohistochemical studies that can confirm the clinical and surgical findings.
dc.language.isoen
dc.publisherE-Century Publishing Corporation
dc.subjectBenign neoplasia
dc.subjectCanalicular adenoma
dc.subjectLip
dc.subjectMinor salivary glands
dc.subjecttumor marker
dc.subjectadenoma
dc.subjectCarcinoma, Adenoid Cystic
dc.subjectcase report
dc.subjectdifferential diagnosis
dc.subjectfemale
dc.subjecthuman
dc.subjectimmunohistochemistry
dc.subjectmiddle aged
dc.subjectSalivary Gland Neoplasms
dc.subjectAdenoma
dc.subjectBiomarkers, Tumor
dc.subjectCarcinoma, Adenoid Cystic
dc.subjectDiagnosis, Differential
dc.subjectFemale
dc.subjectHumans
dc.subjectImmunohistochemistry
dc.subjectMiddle Aged
dc.subjectSalivary Gland Neoplasms
dc.titleMultifocal canalicular adenoma of the minor labial salivary glands
dc.typeArticle


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