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Effects of ashwagandha (Withania somnifera) on vo2max: A systematic review and meta-analysis

dc.contributor.authorPérez-Gómez J.
dc.contributor.authorVillafaina S.
dc.contributor.authorAdsuar J.C.
dc.contributor.authorMerellano-Navarro E.
dc.contributor.authorCollado-Mateo D.
dc.date.accessioned2020-09-02T22:26:24Z
dc.date.available2020-09-02T22:26:24Z
dc.date.issued2020
dc.identifier10.3390/nu12041119
dc.identifier.citation12, 4, -
dc.identifier.issn20726643
dc.identifier.urihttps://hdl.handle.net/20.500.12728/5903
dc.descriptionThe purpose of this study was to systematically review the scientific literature about the effects of supplementation with Ashwagandha (Withania somnifera) on maximum oxygen consumption (VO2max), as well as to provide directions for clinical practice. A systematic search was conducted in three electronic databases following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Guidelines (PRISMA). The inclusion criteria were: (a) VO2max data, with means ± standard deviation before and after the supplement intervention, (b) the study was randomized controlled trial (RCT), (c) the article was written in English. The quality of evidence was evaluated according to the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach. A meta-analysis was performed to determine effect sizes. Five studies were selected in the systematic review (162 participants) and four were included in the meta-analysis (142 participants). Results showed a significant enhancement in VO2max in healthy adults and athletes (p = 0.04). The mean difference was 3.00 (95% CI from 0.18 to 5.82) with high heterogeneity. In conclusion, Ashwagandha supplementation might improve the VO2max in athlete and non-athlete people. However, further research is need to confirm this hypothesis since the number of studies is limited and the heterogeneity was high. © 2020 by the authors. Licensee MDPI, Basel, Switzerland.
dc.language.isoen
dc.publisherMDPI AG
dc.subjectErgogenic aids
dc.subjectMaximum oxygen consumption
dc.subjectPerformance sports
dc.subjectPhysical fitness
dc.subjectadult
dc.subjectaerobic capacity
dc.subjectarticle
dc.subjectathlete
dc.subjectcontrolled study
dc.subjecteffect size
dc.subjectfemale
dc.subjectfitness
dc.subjecthuman
dc.subjecthuman experiment
dc.subjectmale
dc.subjectmeta analysis
dc.subjectnonhuman
dc.subjectPreferred Reporting Items for Systematic Reviews and Meta-Analyses
dc.subjectrandomized controlled trial (topic)
dc.subjectscientific literature
dc.subjectsystematic review
dc.subjectWithania somnifera
dc.titleEffects of ashwagandha (Withania somnifera) on vo2max: A systematic review and meta-analysis
dc.typeArticle


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