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dc.contributor.authorPinto-Ibieta F.
dc.contributor.authorCea M.
dc.contributor.authorCabrera F.
dc.contributor.authorAbanto M.
dc.contributor.authorFelissia F.E.
dc.contributor.authorArea M.C.
dc.contributor.authorCiudad G.
dc.date.accessioned2020-09-02T22:25:51Z
dc.date.available2020-09-02T22:25:51Z
dc.date.issued2020
dc.identifier10.1016/j.biortech.2020.123323
dc.identifier.citation309, , -
dc.identifier.issn09608524
dc.identifier.urihttps://hdl.handle.net/20.500.12728/5810
dc.descriptionHemicellulose hydrolysates (HH), which could be an interesting carbon source to feed mixed microbial cultures (MMC) able to accumulate high value-added compounds. This research focused on the evaluation of a culture strategy to achieve the simultaneous biological production of Levulinic Acid (LA) and Polyhydroxyalcanoates (PHA) by MMC fed with a synthetic HH (SHH). The culture strategy involves the use of sequential batch reactors (SBR) to select microorganisms capable of producing LA and PHA. This work proved that the cultivation strategy used allowed the biological production of LA, reaching 37%w/w when the SHH was composed of 85% pentoses. In addition, the simultaneous biological production of LA and PHB was possible when the SHH was enriched with acetate (45% pentoses − 50% acetate). Finally, this study showed that the composition of the SHH impacts directly on the selected microorganism genus and the type and quantity of the value-added compounds obtained. © 2020 Elsevier Ltd
dc.language.isoen
dc.publisherElsevier Ltd
dc.subjectHemicellulose hydrolysate
dc.subjectLevulinic acid biological production
dc.subjectMixed microbial cultures
dc.subjectPolyhydroxyalkanoates and levulinic acid co-production
dc.subjectBatch reactors
dc.subjectMicroorganisms
dc.subjectOrganic acids
dc.subjectBiological co
dc.subjectBiological production
dc.subjectCarbon source
dc.subjectHemicellulose hydrolysates
dc.subjectLevulinic acid
dc.subjectMixed microbial culture
dc.subjectPolyhydroxyalkanoates
dc.subjectSequential batch reactors
dc.subjectCellulose
dc.subjectacetic acid
dc.subjectcarbohydrate derivative
dc.subjectdissolved oxygen
dc.subjecthemicellulose
dc.subjecthemicellulose hydrolysate
dc.subjectlevulinic acid
dc.subjectpentose
dc.subjectpolyhydroxyalcanoate
dc.subjectpolyhydroxyalkanoic acid
dc.subjectpolymer
dc.subjectunclassified drug
dc.subjectlevulinic acid
dc.subjectpolysaccharide
dc.subjectacetate
dc.subjectbiological production
dc.subjectbioreactor
dc.subjectbiotechnology
dc.subjectcellulose
dc.subjecthydrolysis
dc.subjectmicrobial activity
dc.subjectorganic acid
dc.subjectArticle
dc.subjectbiomass production
dc.subjectbiotechnological procedures
dc.subjectbiotechnological production
dc.subjectcarbon source
dc.subjectchemical composition
dc.subjectevaluation study
dc.subjectmicrobial community
dc.subjectmicrobial culture
dc.subjectmicrobiological examination
dc.subjectmicrobiological phenomena and functions
dc.subjectnonhuman
dc.subjectpriority journal
dc.subjectreactor operation
dc.subjectrenewable resource
dc.subjectbioreactor
dc.subjectCellulose
dc.subjectEvaluation
dc.subjectFeeds
dc.subjectLevulinic Acid
dc.subjectMicroorganisms
dc.subjectOrganic Acids
dc.subjectPentoses
dc.subjectProduction
dc.subjectBioreactors
dc.subjectLevulinic Acids
dc.subjectPolyhydroxyalkanoates
dc.subjectPolysaccharides
dc.titleStrategy for biological co-production of levulinic acid and polyhydroxyalkanoates by using mixed microbial cultures fed with synthetic hemicellulose hydrolysate
dc.typeArticle


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