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Osteonecrosis of the jaw in patient with denosumab therapy

dc.contributor.authorOlate S.
dc.contributor.authorUribe F.
dc.contributor.authorMartinez F.
dc.contributor.authorAlmeida A.
dc.contributor.authorUnibazo A.
dc.date.accessioned2020-09-02T22:24:43Z
dc.date.available2020-09-02T22:24:43Z
dc.date.issued2014
dc.identifier.citation7, 10, 3707-3709
dc.identifier.issn19405901
dc.identifier.urihttps://hdl.handle.net/20.500.12728/5623
dc.descriptionOsteonecrosis (ON) of the jaw has previously been linked to the use of biphosphonates; however, new drugs, also shown similar conditions. This article presents a female patient with mandibular ON related to the use of denosumab. The 55-year-old presented with bone exposure with 8 months of evolution after a dental extraction. The patient began subcutaneous injections of 60 mg denosumab four months prior to the extraction and the lesion remained after the procedure. The patient, with 14 months of follow-up, show mandible ON with no favorable evolution. The clinical condition is presented and the literature of ON associated with denosumab is discussed. © 2014 E-Century Publishing Corporation. All rights reserved.
dc.language.isoen
dc.publisherE-Century Publishing Corporation
dc.subjectCancer therapy
dc.subjectDenosumab
dc.subjectOsteonecrosis
dc.subjectchlorhexidine
dc.subjectdenosumab
dc.subjectadult
dc.subjectArticle
dc.subjectbone lesion
dc.subjectbone pain
dc.subjectbreast carcinoma
dc.subjectcancer chemotherapy
dc.subjectcase report
dc.subjectfemale
dc.subjecthuman
dc.subjectjaw osteonecrosis
dc.subjectlymph node dissection
dc.subjectmastectomy
dc.subjectmiddle aged
dc.subjectradiation dose
dc.subjecttransitional cell carcinoma
dc.titleOsteonecrosis of the jaw in patient with denosumab therapy
dc.typeArticle


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