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Key factors associated with uncontrolled asthma–the Asthma Control in Latin America Study

dc.contributor.authorNeffen H.
dc.contributor.authorChahuàn M.
dc.contributor.authorHernández D.D.
dc.contributor.authorVallejo-Perez E.
dc.contributor.authorBolivar F.
dc.contributor.authorSánchez M.H.
dc.contributor.authorGalleguillos F.
dc.contributor.authorCastaños C.
dc.contributor.authorS.Silva R.
dc.contributor.authorGiugno E.
dc.contributor.authorPavie J.
dc.contributor.authorContreras R.
dc.contributor.authorLamarao F.
dc.contributor.authorMoraes dos Santos F.
dc.contributor.authorRodriguez C.
dc.contributor.authorTobler J.
dc.contributor.authorViana K.
dc.contributor.authorVieira C.
dc.contributor.authorSoares C.
dc.date.accessioned2020-09-02T22:24:17Z
dc.date.available2020-09-02T22:24:17Z
dc.date.issued2020
dc.identifier10.1080/02770903.2018.1553050
dc.identifier.citation57, 2, 113-122
dc.identifier.issn02770903
dc.identifier.urihttps://hdl.handle.net/20.500.12728/5563
dc.descriptionObjective: This study aimed to estimate asthma control at specialist treatment centers in four Latin American countries and assess factors influencing poor asthma control. Methods: Patients aged ≥12 years with an asthma diagnosis and asthma medication prescription, followed at outpatient specialist centers in Argentina, Chile, Colombia, and Mexico, were included. The study received all applicable ethical approvals. The Asthma Control Test (ACT) was used to classify patients as having controlled (ACT 20–25) or uncontrolled (ACT ≤19) asthma. Frequency and statistical tests were used to assess the association between hospital admissions/exacerbations/emergency department (ED) visits and uncontrolled asthma; multivariate logistic regression was used to assess the association of uncontrolled asthma with clinical/demographic variables. Results: A total of 594 patients were included. Overall controlled-asthma prevalence was 43.4% (95% confidence interval [CI]: 39.0, 47.4). Patients with uncontrolled asthma were more likely to be women (adjusted odds ratio [aOR]: 1.85; p = 0.003), non-white (aOR: 2.14; p < 0.001), obese (aOR: 1.71; p = 0.036), to have a low monthly family income (aOR: 1.75; p = 0.004), to have severe asthma (aOR:1.59; p = 0.26), and, compared with patients with controlled asthma, to have a higher likelihood of asthma exacerbations (34.5% vs. 15.9%; p < 0.001), hospital admissions (6.9% vs. 3.1%; p = 0.042), and ED visits (34.5% vs. 15.9%; p < 0.001) due to asthma. Conclusions: Even in specialist ambulatory services, fewer than half of patients were classified as having controlled asthma. The proportion of uncontrolled patients varied according to clinical and demographic variables. © 2019, © 2019 The Author(s). Published with license by Taylor & Francis Group, LLC.
dc.language.isoen
dc.publisherTaylor and Francis Ltd
dc.subjectACT
dc.subjectasthma exacerbations
dc.subjectemergency department visits
dc.subjecthospital admissions
dc.subjectLatin American countries
dc.subjectOutpatient specialist centers
dc.subjectadrenergic receptor stimulating agent
dc.subjectantihistaminic agent
dc.subjectcholinergic receptor blocking agent
dc.subjectcorticosteroid
dc.subjectimmunoglobulin E antibody
dc.subjectleukotriene receptor blocking agent
dc.subjectxanthine derivative
dc.subjectadolescent
dc.subjectadult
dc.subjectaged
dc.subjectArgentina
dc.subjectArticle
dc.subjectasthma
dc.subjectAsthma Control Test
dc.subjectchild
dc.subjectChile
dc.subjectColombia
dc.subjectdisease control
dc.subjectdisease exacerbation
dc.subjectemergency care
dc.subjectfemale
dc.subjecthospital admission
dc.subjecthuman
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectMexico
dc.subjectmiddle aged
dc.subjectmulticenter study
dc.subjectschool child
dc.subjectyoung adult
dc.titleKey factors associated with uncontrolled asthma–the Asthma Control in Latin America Study
dc.typeArticle


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