Increased lipoprotein(a) in a paediatric patient associated with nephrotic syndrome [Incremento de lipoproteína(a) en paciente pediátrico asociado a síndrome nefrótico]
Autor
Menéndez Valladares P.
Arrobas Velilla T.
Bermúdez de la Vega J.A.
Romero Pérez M.D.M.
Fabiani Romero F.
González Rodríguez C.
Resumen
A common complication in paediatric patients with nephrotic syndrome (NS) is hyperlipidaemia. About 20% of children do not respond to treatment with corticosteroids, presenting with a cortico-resistant NS (CRNS), which can progress to kidney failure. It has been observed that paediatric patients with CRNS have an elevated low density lipoprotein cholesterol (LDL-c), very low density lipoprotein cholesterol (VLDL-c), and triglycerides levels, as well as elevated Lipoprotein-a [Lp (a)] levels. The case is presented of a 5 year old boy, diagnosed with CRNS, presenting with dyslipidaemia with increased LDL-c, Apo-B100, and Lp(a) levels. After the poor prognosis of the renal function, immunosuppressant treatment was started with tacrolimus and atorvastatin to control dyslipidaemia. Although tacrolimus causes an elevation of total cholesterol and LDL-c, the significant alterations of the children lipid profile suggest the existence of a high cardiovascular risk. In these cases, it would be interesting to have reference values in children in our health area. © 2016 Sociedad Española de Arteriosclerosis
Colecciones
Ítems relacionados
Mostrando ítems relacionados por Título, autor o materia.
-
Article
Gender differences on effectiveness of a school-based physical activity intervention for reducing cardiometabolic risk: A cluster randomized trial (2020)
Martínez-Vizcaíno V.; Sánchez-López M.; Notario-Pacheco B.; Salcedo-Aguilar F.; Solera-Martínez M.; Franquelo-Morales P.; López-Martínez S.; García-Prieto J.C.; Arias-Palencia N.; Torrijos-Niño C.; ... (BioMed Central Ltd., 2014) -
Review
Modulation of heat shock proteins by statins (2020)
Forouzanfar F.; Butler A.E.; Banach M.; Barreto G.E.; Sahbekar A. (Academic Press, 2018) -
Article
Psoriasis vulgaris with or without arthritis and independent of disease severity or duration is a risk factor for hypercholesterolemia (2020)
Santos-Juanes J.; Coto-Segura P.; Fernández-Vega I.; Armesto S.; Martínez-Camblor P. (S. Karger AG, 2015)