Mostrar el registro sencillo del ítem

Glial modulation by N-acylethanolamides in brain injury and neurodegeneration

dc.contributor.authorHerrera M.I.
dc.contributor.authorKölliker-Frers R.
dc.contributor.authorBarreto G.
dc.contributor.authorBlanco E.
dc.contributor.authorCapani F.
dc.date.accessioned2020-09-02T22:20:26Z
dc.date.available2020-09-02T22:20:26Z
dc.date.issued2016
dc.identifier10.3389/fnagi.2016.00081
dc.identifier.citation8, APR, -
dc.identifier.issn16634365
dc.identifier.urihttps://hdl.handle.net/20.500.12728/4873
dc.descriptionNeuroinflammation involves the activation of glial cells and represents a key element in normal aging and pathophysiology of brain damage. N-acylethanolamides (NAEs), naturally occurring amides, are known for their pro-homeostatic effects. An increase in NAEs has been reported in vivo and in vitro in the aging brain and in brain injury. Treatment with NAEs may promote neuroprotection and exert anti-inflammatory actions via PPARα activation and/or by counteracting gliosis. This review aims to provide an overview of endogenous and exogenous properties of NAEs in neuroinflammation and to discuss their interaction with glial cells. © 2016 Herrera, Kölliker-Frers, Barreto, Blanco and Capani.
dc.language.isoen
dc.publisherFrontiers Media S.A.
dc.subjectGliosis
dc.subjectN-acylethanolamides
dc.subjectNeuroinflammation
dc.subjectNeuroprotection
dc.subjectPPARα
dc.subjectamide
dc.subjectanandamide
dc.subjectn acylethanolamide derivative
dc.subjectn oleoylethanolamine
dc.subjectpalmidrol
dc.subjectperoxisome proliferator activated receptor
dc.subjectunclassified drug
dc.subjectaging
dc.subjectAlzheimer disease
dc.subjectantiinflammatory activity
dc.subjectastrocyte
dc.subjectastrocytosis
dc.subjectbrain injury
dc.subjectbrain ischemia
dc.subjectcell activation
dc.subjectcell interaction
dc.subjectcerebrovascular accident
dc.subjectdegenerative disease
dc.subjectdrug efficacy
dc.subjectdrug structure
dc.subjectglia cell
dc.subjectgliosis
dc.subjecthuman
dc.subjectlearning disorder
dc.subjectmemory disorder
dc.subjectmicroglia
dc.subjectnerve degeneration
dc.subjectnervous system inflammation
dc.subjectneuromodulation
dc.subjectneuroprotection
dc.subjectnonhuman
dc.subjectParkinson disease
dc.subjectpathophysiology
dc.subjectperinatal asphyxia
dc.subjectperipheral neuropathy
dc.subjectpleiotropy
dc.subjectreceptor upregulation
dc.subjectShort Survey
dc.subjectsignal transduction
dc.subjectspinal cord injury
dc.subjecttraumatic brain injury
dc.titleGlial modulation by N-acylethanolamides in brain injury and neurodegeneration
dc.typeShort Survey


Ficheros en el ítem

Thumbnail
Nombre:
item_2-s2.0-84974588687.pdf
Tamaño:
3.048Kb
Formato:
PDF
Ver/

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem