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Zinc oxide and copper nanoparticles addition in universal adhesive systems improve interface stability on caries-affected dentin
dc.contributor.author | Gutiérrez M.F. | |
dc.contributor.author | Bermudez J. | |
dc.contributor.author | Dávila-Sánchez A. | |
dc.contributor.author | Alegría-Acevedo L.F. | |
dc.contributor.author | Méndez-Bauer L. | |
dc.contributor.author | Hernández M. | |
dc.contributor.author | Astorga J. | |
dc.contributor.author | Reis A. | |
dc.contributor.author | Loguercio A.D. | |
dc.contributor.author | Farago P.V. | |
dc.contributor.author | Fernández E. | |
dc.date.accessioned | 2020-09-02T22:19:54Z | |
dc.date.available | 2020-09-02T22:19:54Z | |
dc.date.issued | 2019 | |
dc.identifier | 10.1016/j.jmbbm.2019.07.024 | |
dc.identifier.citation | 100, , - | |
dc.identifier.issn | 17516161 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12728/4804 | |
dc.description | This study evaluated the MMP inhibition of the zinc oxide and copper nanoparticles (ZnO/CuNp), and the effects of their addition into adhesives on antimicrobial activity (AMA), ultimate tensile strength (UTS), in vitro degree of conversion (in vitro-DC), as well as, resin–dentin bond strength (μTBS), nanoleakage (NL) and in situ-DC on caries-affected dentin. Anti-MMP activity was evaluated for several MMPs. ZnO/CuNp (0% [control]; 5/0.1 and 5/0.2 wt%) were added into Prime&Bond Active (PBA) and Ambar Universal (AMB). The AMA was evaluated against Streptococcus mutans. UTS were tested after 24 h and 28d. After induced caries, adhesives and composite were applied to flat dentin surfaces, and specimens were sectioned to obtain resin–dentin sticks. μTBS, NL, in vitro-DC and in situ-DC were evaluated after 24 h. ANOVA and Tukey's test were applied (α = 0.05). ZnO/CuNp demonstrated anti-MMP activity (p < 0.05). The addition of ZnO/CuNp increased AMA and UTS (AMB; p < 0.05). UTS for PBA, in vitro-DC, in situ-DC and μTBS for both adhesives were maintained with ZnO/CuNp (p > 0.05). However, lower NL was observed for ZnO/CuNp groups (p < 0.05). The addition of ZnO/CuNp in adhesives may be an alternative to provide antimicrobial, anti-MMP activities and improves the integrity of the hybrid layer on caries-affected dentin. © 2019 Elsevier Ltd | |
dc.language.iso | en | |
dc.publisher | Elsevier Ltd | |
dc.subject | Copper | |
dc.subject | Microtensile bond strength | |
dc.subject | Nanoleakage | |
dc.subject | Nanoparticles | |
dc.subject | Universal adhesive system | |
dc.subject | Zinc oxide | |
dc.subject | Bond strength (materials) | |
dc.subject | Copper | |
dc.subject | II-VI semiconductors | |
dc.subject | Metal nanoparticles | |
dc.subject | Microorganisms | |
dc.subject | Nanoparticles | |
dc.subject | Resins | |
dc.subject | Tensile strength | |
dc.subject | Zinc oxide | |
dc.subject | Anti-microbial activity | |
dc.subject | Degree of conversion | |
dc.subject | Interface stabilities | |
dc.subject | Micro-tensile bond strength | |
dc.subject | Nanoleakages | |
dc.subject | Streptococcus mutans | |
dc.subject | Ultimate tensile strength | |
dc.subject | Universal adhesives | |
dc.subject | Adhesives | |
dc.subject | adhesive agent | |
dc.subject | copper nanoparticle | |
dc.subject | zinc oxide nanoparticle | |
dc.subject | adult | |
dc.subject | antimicrobial activity | |
dc.subject | Article | |
dc.subject | confocal laser scanning microscopy | |
dc.subject | controlled study | |
dc.subject | dental caries | |
dc.subject | dentin | |
dc.subject | human | |
dc.subject | in vitro study | |
dc.subject | priority journal | |
dc.subject | Streptococcus mutans | |
dc.subject | tensile strength | |
dc.title | Zinc oxide and copper nanoparticles addition in universal adhesive systems improve interface stability on caries-affected dentin | |
dc.type | Article |