Mostrar el registro sencillo del ítem

Liberal red blood cell transfusions impair quality of life after cardiac surgery [La transfusión liberal de concentrado de hematíes deteriora la calidad de vida después de la cirugía cardíaca]

dc.contributor.authorGonzález-Pérez A.
dc.contributor.authorAl-Sibai J.Z.
dc.contributor.authorÁlvarez-Fernández P.
dc.contributor.authorMartínez-Camblor P.
dc.contributor.authorArgüello-Junquera M.
dc.contributor.authorGarcía-Gala J.M.
dc.contributor.authorMartínez-Revuelta E.
dc.contributor.authorSilva J.
dc.contributor.authorMorís C.
dc.contributor.authorAlbaiceta G.M.
dc.date.accessioned2020-09-02T22:19:24Z
dc.date.available2020-09-02T22:19:24Z
dc.date.issued2019
dc.identifier10.1016/j.medin.2018.01.014
dc.identifier.citation43, 3, 156-164
dc.identifier.issn02105691
dc.identifier.urihttps://hdl.handle.net/20.500.12728/4729
dc.descriptionBackground: The optimal blood management after cardiac surgery remains controversial. Moreover, blood transfusions may have an impact on long-term outcomes. Objective: The aim of this study is to characterize the impact of liberal red blood cell transfusions on Health-Related Quality of life (HRQoL) after cardiac surgery. Methods: We studied a cohort of 205 consecutive patients after ICU discharge. Baseline characteristics and clinical data were recorded, and HRQoL was assessed using the EuroQoL-5D instrument, applied 6 months after ICU discharge. A specific question regarding the improvement in the quality of life after the surgical intervention was added to the HRQoL questionnaire. Risk factors related to impaired quality of life were identified using univariate comparisons and multivariate regression techniques. Results: The median (interquartile range, IQR) of transfused red blood cells was 3 (1–4). Among 205 patients, 178 were studied 6 months after discharge. Impairment in at least one dimension of the EuroQoL-5D questionnaire was observed in 120 patients, with an overall score of 0.8 (IQR 0.61–1). The number of red blood cell transfusions was related to an impaired HRQoL (OR 1.17 per additional unit, 95% confidence interval 1.03–1.36, p = 0.03), a trend to lower visual analog scale score (coefficient −0.75 per additional unit, 95% confidence interval −1.61 to 0.1, p = 0.09) and an absence of improvement in HRQoL after surgery compared to the previous status (OR 1.13, 95% confidence interval 1.03–1.25, p = 0.01). Conclusions: Liberal red blood cell transfusions increase the risk of impaired HRQoL after cardiac surgery. © 2018 Elsevier España, S.L.U. y SEMICYUC
dc.language.isoen
dc.language.isoes
dc.publisherEdiciones Doyma, S.L.
dc.subjectBlood transfusions
dc.subjectCardiac surgery
dc.subjectHealth-related quality of life
dc.subjectIntensive care unit outcomes
dc.subjectadult
dc.subjectarticle
dc.subjectcohort analysis
dc.subjecterythrocyte transfusion
dc.subjectfemale
dc.subjectheart surgery
dc.subjecthuman
dc.subjecthuman cell
dc.subjectintensive care unit
dc.subjectintermethod comparison
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectquality of life
dc.subjectquestionnaire
dc.subjectrisk factor
dc.subjectsurgery
dc.subjectvisual analog scale
dc.subjectadverse event
dc.subjectaged
dc.subjecterythrocyte transfusion
dc.subjectpostoperative period
dc.subjectprocedures
dc.subjectprospective study
dc.subjectregression analysis
dc.subjecttime factor
dc.subjectAged
dc.subjectCardiac Surgical Procedures
dc.subjectErythrocyte Transfusion
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectPostoperative Period
dc.subjectProspective Studies
dc.subjectQuality of Life
dc.subjectRegression Analysis
dc.subjectRisk Factors
dc.subjectSurveys and Questionnaires
dc.subjectTime Factors
dc.titleLiberal red blood cell transfusions impair quality of life after cardiac surgery [La transfusión liberal de concentrado de hematíes deteriora la calidad de vida después de la cirugía cardíaca]
dc.typeArticle


Ficheros en el ítem

Thumbnail
Nombre:
item_2-s2.0-85043477030.pdf
Tamaño:
3.75Kb
Formato:
PDF
Ver/

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem