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Muscular Strength as a Predictor of All-Cause Mortality in an Apparently Healthy Population: A Systematic Review and Meta-Analysis of Data From Approximately 2 Million Men and Women
dc.contributor.author | García-Hermoso A. | |
dc.contributor.author | Cavero-Redondo I. | |
dc.contributor.author | Ramírez-Vélez R. | |
dc.contributor.author | Ruiz J.R. | |
dc.contributor.author | Ortega F.B. | |
dc.contributor.author | Lee D.-C. | |
dc.contributor.author | Martínez-Vizcaíno V. | |
dc.date.accessioned | 2020-09-02T22:18:47Z | |
dc.date.available | 2020-09-02T22:18:47Z | |
dc.date.issued | 2018 | |
dc.identifier | 10.1016/j.apmr.2018.01.008 | |
dc.identifier.citation | 99, 10, 2100-2113.e5 | |
dc.identifier.issn | 00039993 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12728/4622 | |
dc.description | Objectives: The aims of the present systematic review and meta-analysis were to determine the relationship between muscular strength and all-cause mortality risk and to examine the sex-specific impact of muscular strength on all-cause mortality in an apparently healthy population. Data Sources: Two authors systematically searched MEDLINE, EMBASE and SPORTDiscus databases and conducted manual searching of reference lists of selected articles. Study Selection: Eligible cohort studies were those that examined the association of muscular strength with all-cause mortality in an apparently healthy population. The hazard ratio (HR) estimates with 95% confidence interval (CI) were pooled by using random effects meta-analysis models after assessing heterogeneity across studies. Data Extraction: Two authors independently extracted data. Data Synthesis: Thirty-eight studies with 1,907,580 participants were included in the meta-analysis. The included studies had a total of 63,087 deaths. Higher levels of handgrip strength were associated with a reduced risk of all-cause mortality (HR=0.69; 95% CI, 0.64-0.74) compared with lower muscular strength, with a slightly stronger association in women (HR=0.60; 95% CI, 0.51-0.69) than men (HR=0.69; 95% CI, 0.62-0.77) (all P<.001). Also, adults with higher levels of muscular strength, as assessed by knee extension strength test, had a 14% lower risk of death (HR=0.86: 95% CI, 0.80-0.93; P<.001) compared with adults with lower muscular strength. Conclusions: Higher levels of upper- and lower-body muscular strength are associated with a lower risk of mortality in adult population, regardless of age and follow-up period. Muscular strength tests can be easily performed to identify people with lower muscular strength and, consequently, with an increased risk of mortality. © 2018 American Congress of Rehabilitation Medicine | |
dc.language.iso | en | |
dc.publisher | W.B. Saunders | |
dc.subject | Death | |
dc.subject | Hand strength | |
dc.subject | Leg strength | |
dc.subject | Muscles | |
dc.subject | adult | |
dc.subject | all cause mortality | |
dc.subject | article | |
dc.subject | cohort analysis | |
dc.subject | controlled study | |
dc.subject | data extraction | |
dc.subject | data synthesis | |
dc.subject | death | |
dc.subject | Embase | |
dc.subject | female | |
dc.subject | follow up | |
dc.subject | grip strength | |
dc.subject | hazard ratio | |
dc.subject | human | |
dc.subject | knee | |
dc.subject | male | |
dc.subject | Medline | |
dc.subject | meta analysis | |
dc.subject | mortality risk | |
dc.subject | muscle strength | |
dc.subject | risk assessment | |
dc.subject | systematic review | |
dc.subject | aged | |
dc.subject | cause of death | |
dc.subject | health survey | |
dc.subject | middle aged | |
dc.subject | mortality | |
dc.subject | muscle disease | |
dc.subject | muscle strength | |
dc.subject | pathophysiology | |
dc.subject | physiology | |
dc.subject | proportional hazards model | |
dc.subject | sex ratio | |
dc.subject | Adult | |
dc.subject | Aged | |
dc.subject | Cause of Death | |
dc.subject | Cohort Studies | |
dc.subject | Female | |
dc.subject | Humans | |
dc.subject | Male | |
dc.subject | Middle Aged | |
dc.subject | Muscle Strength | |
dc.subject | Muscular Diseases | |
dc.subject | Population Surveillance | |
dc.subject | Proportional Hazards Models | |
dc.subject | Sex Distribution | |
dc.title | Muscular Strength as a Predictor of All-Cause Mortality in an Apparently Healthy Population: A Systematic Review and Meta-Analysis of Data From Approximately 2 Million Men and Women | |
dc.type | Review |