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Pacinian Corpuscles in Human Lymph Nodes

dc.contributor.authorFeito J.
dc.contributor.authorCobo J.L.
dc.contributor.authorSantos-Briz A.
dc.contributor.authorVega J.A.
dc.date.accessioned2020-09-02T22:17:25Z
dc.date.available2020-09-02T22:17:25Z
dc.date.issued2017
dc.identifier10.1002/ar.23679
dc.identifier.citation300, 12, 2233-2238
dc.identifier.issn19328486
dc.identifier.urihttps://hdl.handle.net/20.500.12728/4431
dc.descriptionThe occurrence of Pacinian corpuscles associated to lymph nodes is an anatomical rarity and very scarce information exists in this regard. Here we examined immunohistochemically four Pacinian corpuscles found in the close vicinity of the hiliar blood vessels of lymph nodes (2 cervical, 1 axillary, and 1 inguinal) during routine surgical pathology. Pacinian corpuscles were normally arranged and displayed a pattern of protein distribution as follows: the axon was positive for neurofilament proteins and neuron specific enolase, the inner core cells showed intense S100 protein and vimentin immunostaining while they were negative for glial fibrillary acidic protein, type IV collagen and glucose transporter 1; vimentin, type IV collagen, and glucose transporter 1 were also observed also in the outer-core and the capsule. These results are in agreement with those reported for cutaneous Pacinian corpuscles, demonstrating that the immunohistochemical profile of these corpuscles is independent of its anatomical localization. The possible functional significance of Pacinian corpuscles in lymph nodes is discussed. Anat Rec, 300:2233–2238, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.
dc.language.isoen
dc.publisherBlackwell Publishing Inc.
dc.subjecthuman
dc.subjectimmunohistochemical profile
dc.subjectlymph nodes
dc.subjectPacinian corpuscles
dc.subjectcollagen type 4
dc.subjectglial fibrillary acidic protein
dc.subjectglucose transporter 1
dc.subjectneurofilament protein
dc.subjectneuron specific enolase
dc.subjectprotein S 100
dc.subjectvimentin
dc.subjectArticle
dc.subjectaxon
dc.subjectblood vessel
dc.subjectendothelium cell
dc.subjecthuman
dc.subjecthuman tissue
dc.subjectimmunohistochemistry
dc.subjectimmunoreactivity
dc.subjectlymph node
dc.subjectPacini corpuscle
dc.subjectpriority journal
dc.subjectprotein expression
dc.subjectprotein localization
dc.subjecttissue distribution
dc.subjectacquired immune deficiency syndrome
dc.subjectaged
dc.subjectcase report
dc.subjectinguinal hernia
dc.subjectlymph node
dc.subjectmiddle aged
dc.subjectneoplasm
dc.subjectPacini corpuscle
dc.subjectpathology
dc.subjectvery elderly
dc.subjectAcquired Immunodeficiency Syndrome
dc.subjectAged
dc.subjectAged, 80 and over
dc.subjectHernia, Inguinal
dc.subjectHumans
dc.subjectLymph Nodes
dc.subjectMiddle Aged
dc.subjectNeoplasms
dc.subjectPacinian Corpuscles
dc.titlePacinian Corpuscles in Human Lymph Nodes
dc.typeArticle


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