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Comparison between conventional sutures with ulmoplus® and without ulmoplus® in the incision closure of rabbit skin (Oryctolagus cuniculus) [Comparación entre suturas convencional coadyuvada con ulmoplus® y sin ulmoplus® en el cierre de incisiones de piel de conejo (Oryctolagus cuniculus)]

dc.contributor.authorEspín L.
dc.contributor.authorVásquez B.
dc.contributor.authorSchencke C.
dc.contributor.authorDel Sol M.
dc.date.accessioned2020-09-02T22:17:19Z
dc.date.available2020-09-02T22:17:19Z
dc.date.issued2019
dc.identifier10.4067/S0717-95022019000301073
dc.identifier.citation37, 3, 1073-1078
dc.identifier.issn07179367
dc.identifier.urihttps://hdl.handle.net/20.500.12728/4396
dc.descriptionConsidering the advances in research that relate honey therapeutic effects in wound healing process, the present investigation aimed to evaluate and compare qualitatively, through morphological analysis, the local tissue response between conventional suture with Ulmoplus ® and without Ulmoplus ® in the closure of the rabbit skin incision. We used 10 adult rabbits, divided into group S (suture) and group S + U (suture plus Ulmoplus®). An 10 mm long incision was made in the anterior region of the leg, passing through epidermis and dermis, until reaching the deep fascia that covered the anterior tibial muscle. Subsequently, only the S + U group was given Ulmoplus®. Then, in both groups, the incision was sutured with two intradermal points of polyglycolic acid (vicryl 2/0). After 10 days post incision, biopsies of the skin were taken and processed for observation in a light microscope. The study was carried out considering the recommendations of the Guide for the Care and Use of Laboratory Animals. Both groups had a closed incision at day 10 with microscopic characteristics of a proliferative phase. However, the S + U group showed a scar of shorter length and flatter appearance, whose epidermis was more organized and thinner, with differentiated basal cells. At the dermal level, wound contraction was observed, evidencing a smaller scar area. Ulmoplus®, as a coadjuvant in closing surgical wounds process using conventional suture is a good alternative, since it accelerates the healing process and allows better aesthetic results of the scar. © 2019, Universidad de la Frontera. All rights reserved.
dc.language.isoes
dc.publisherUniversidad de la Frontera
dc.subjectHealing
dc.subjectIncision
dc.subjectRabbit
dc.subjectSuture
dc.subjectUlmoplus®
dc.titleComparison between conventional sutures with ulmoplus® and without ulmoplus® in the incision closure of rabbit skin (Oryctolagus cuniculus) [Comparación entre suturas convencional coadyuvada con ulmoplus® y sin ulmoplus® en el cierre de incisiones de piel de conejo (Oryctolagus cuniculus)]
dc.typeArticle


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