Mostrar el registro sencillo del ítem

Multiple Ribosomal RNA operons in bacteria; Their concerted evolution and potential consequences on the rate of evolution of their 16S rRNA

dc.contributor.authorEspejo R.T.
dc.contributor.authorPlaza N.
dc.date.accessioned2020-09-02T22:17:18Z
dc.date.available2020-09-02T22:17:18Z
dc.date.issued2018
dc.identifier10.3389/fmicb.2018.01232
dc.identifier.citation9, JUN, -
dc.identifier.issn1664302X
dc.identifier.urihttps://hdl.handle.net/20.500.12728/4391
dc.descriptionBacterial species differ greatly in the number and location of the rRNA operons which may be present in the bacterial chromosomes and plasmids. Most bacterial species contain more than one ribosomal RNA operon copy in their genomes, with some species containing up to 15 such copies. We review the number and location of the rRNA operons and discuss evolution of 16S rRNA (rrs) genes -which are considered as ultimate chronometers for phylogenetic classification- in bacteria with multiple copies of these genes. In these bacterial species, the rrs genes must evolve in concert and sequence changes generated by mutation or horizontal gene transfer must be either erased or spread to every gene copy to avoid divergence, as it occurs when they are present in different species. Analysis of polymorphic sites in intra-genomic rrs copies identifies putative conversion events and demonstrates that sequence conversion is patchy and occurs in small conversion tracts. Sequence conversion probably arises by a non-reciprocal transfer between two or more copies where one copy contributes only a small contiguous segment of DNA, whereas the other copy contributes the rest of the genome in a fairly well understood molecular process. Because concerted evolution implies that a mutation in any of the rrs copies is either eliminated or transferred to every rrs gene in the genome, this process should slow their evolution rate relative to that of single copy genes. However, available data on the rrs genes in bacterial genomes do not show a clear relationship between their evolution rates and the number of their copies in the genome. © 2018 Espejo and Plaza.
dc.language.isoen
dc.publisherFrontiers Media S.A.
dc.subject16S rRNA
dc.subjectConcerted
dc.subjectEvolution
dc.subjectMultiple-copies
dc.subjectPolymorphism
dc.subjectRrs
dc.subjectribosome RNA
dc.subjectRNA 16S
dc.subjectbacterial gene
dc.subjectbacterium
dc.subjectgene mutation
dc.subjecthorizontal gene transfer
dc.subjectmolecular evolution
dc.subjectnonhuman
dc.subjectoperon
dc.subjectphylogeny
dc.subjectShort Survey
dc.titleMultiple Ribosomal RNA operons in bacteria; Their concerted evolution and potential consequences on the rate of evolution of their 16S rRNA
dc.typeShort Survey


Ficheros en el ítem

Thumbnail
Nombre:
item_2-s2.0-85048268341.pdf
Tamaño:
2.787Kb
Formato:
PDF
Ver/

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem