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Orange beverage ameliorates high-fat-diet-induced metabolic disorder in mice

dc.contributor.authorEscudero-López B.
dc.contributor.authorFernández-Pachón M.S.
dc.contributor.authorHerrero-Martín G.
dc.contributor.authorOrtega Á.
dc.contributor.authorCerrillo I.
dc.contributor.authorMartín F.
dc.contributor.authorBerná G.
dc.date.accessioned2020-09-02T22:17:18Z
dc.date.available2020-09-02T22:17:18Z
dc.date.issued2016
dc.identifier10.1016/j.jff.2016.04.013
dc.identifier.citation24, , 254-263
dc.identifier.issn17564646
dc.identifier.urihttps://hdl.handle.net/20.500.12728/4387
dc.descriptionMetabolic syndrome (MetS) refers to a group of disorders that includes insulin resistance, central obesity, arterial hypertension and hyperlipidaemia. Regular consumption of bioactive compounds has consistently been associated with a reduced risk of these disorders. The aim of this study was to determine if an orange beverage with high concentrations of bioactive compounds (flavanones, carotenoids, melatonin, and ascorbic acid) and low alcohol content (<1%, v/v) improves metabolic parameters through modulation of oxidative stress, lipid profile and inflammatory response in a rodent model of high fat diet (HFD)-induced obesity. Mice with HFD-induced MetS were fed the orange beverage for 12 weeks (volume equivalent to 250 mL/day in human). Long-term intake of the orange beverage decreased plasma TAG, oxidized LDL and C-reactive protein levels. The present data provide evidence of a beneficial effect of orange beverage intake on some outcome parameters related to HFD-induced MetS. © 2016 Elsevier Ltd.
dc.language.isoen
dc.publisherElsevier Ltd
dc.subjectAntioxidant status
dc.subjectBioactive compounds
dc.subjectFermented orange juice
dc.subjectHFD
dc.subjectLipid profile
dc.subjectMetabolic syndrome
dc.titleOrange beverage ameliorates high-fat-diet-induced metabolic disorder in mice
dc.typeArticle


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