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Disease prevention: An opportunity to expand edible plant-based vaccines?

dc.contributor.authorConcha C.
dc.contributor.authorCañas R.
dc.contributor.authorMacuer J.
dc.contributor.authorTorres M.J.
dc.contributor.authorHerrada A.A.
dc.contributor.authorJamett F.
dc.contributor.authorIbáñez C.
dc.date.accessioned2020-09-02T22:15:00Z
dc.date.available2020-09-02T22:15:00Z
dc.date.issued2017
dc.identifier10.3390/vaccines5020014
dc.identifier.citation5, 2, -
dc.identifier.issn2076393X
dc.identifier.urihttps://hdl.handle.net/20.500.12728/4067
dc.descriptionThe lethality of infectious diseases has decreased due to the implementation of crucial sanitary procedures such as vaccination. However, the resurgence of pathogenic diseases in different parts of the world has revealed the importance of identifying novel, rapid, and concrete solutions for control and prevention. Edible vaccines pose an interesting alternative that could overcome some of the constraints of traditional vaccines. The term “edible vaccine” refers to the use of edible parts of a plant that has been genetically modified to produce specific components of a particular pathogen to generate protection against a disease. The aim of this review is to present and critically examine “edible vaccines” as an option for global immunization against pathogenic diseases and their outbreaks and to discuss the necessary steps for their production and control and the list of plants that may already be used as edible vaccines. Additionally, this review discusses the required standards and ethical regulations as well as the advantages and disadvantages associated with this powerful biotechnology tool. © 2017 by the authors. Licensee MDPI, Basel, Switzerland.
dc.language.isoen
dc.publisherMDPI AG
dc.subjectDisease outbreaks
dc.subjectEdible vaccine
dc.subjectFood biotechnology
dc.subjectGenetic modification
dc.subjectImmunogenicity
dc.subjectMedicinal food
dc.subjectalgal extract
dc.subjectCarica papaya extract
dc.subjectedible vaccine
dc.subjectimmunoglobulin A
dc.subjectsevere acute respiratory syndrome vaccine
dc.subjectWart virus vaccine
dc.subjectAgrobacterium tumefaciens
dc.subjectalfalfa
dc.subjectapple
dc.subjectbanana
dc.subjectcarrot
dc.subjectCorynebacterium diphtheriae
dc.subjectdendritic cell
dc.subjectdiphtheria
dc.subjectDNA modification
dc.subjectfood biotechnology
dc.subjectHepatitis B virus
dc.subjecthuman
dc.subjectimmune response
dc.subjectimmunological tolerance
dc.subjectinfectious disease medicine
dc.subjectlettuce
dc.subjectmaize
dc.subjectmarginal zone lymphoma
dc.subjectMink enteritis virus
dc.subjectNicotiana benthamiana
dc.subjectnonhuman
dc.subjectpapaya
dc.subjectpathogenesis
dc.subjectplant genome
dc.subjectpotato
dc.subjectprotein expression
dc.subjectprotein purification
dc.subjectReview
dc.subjectrice
dc.subjectsevere acute respiratory syndrome
dc.subjectsoybean
dc.subjecttobacco
dc.subjecttomato
dc.subjecttransgenic plant
dc.subjectvaccination
dc.subjectvaccine immunogenicity
dc.subjectZika virus
dc.titleDisease prevention: An opportunity to expand edible plant-based vaccines?
dc.typeReview


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