Mostrar el registro sencillo del ítem

Glycated haemoglobin A1c as a predictor of preeclampsia in type 1 diabetic pregnant women: A systematic review and meta-analysis

dc.contributor.authorCavero-Redondo I.
dc.contributor.authorMartínez-Vizcaíno V.
dc.contributor.authorSoriano-Cano A.
dc.contributor.authorMartínez-Hortelano J.A.
dc.contributor.authorSanabria-Martínez G.
dc.contributor.authorÁlvarez-Bueno C.
dc.date.accessioned2020-09-02T22:14:51Z
dc.date.available2020-09-02T22:14:51Z
dc.date.issued2018
dc.identifier10.1016/j.preghy.2018.04.004
dc.identifier.citation14, , 49-54
dc.identifier.issn22107789
dc.identifier.urihttps://hdl.handle.net/20.500.12728/4015
dc.descriptionObjective: To examine the relationship between the increase of glycated haemoglobin A1c (HbA1c) levels and the risk of preeclampsia in pregnant with type 1 diabetes mellitus; and to determine from which trimester the increase of HbA1c levels better predicts the risk of suffering preeclampsia in type 1 diabetic pregnant women. Methods: We systematically searched MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials, the Cochrane Database of Systematic Reviews and Web of Science databases, from inception to May 2017, for observational studies addressing the association of HbA1c levels with preeclampsia. Fixed effects models were used to compute pooled estimates of odds ratio (OR) and respective 95% confidence intervals (95% CI) for preeclampsia in type 1 diabetic pregnant women. Additionally, subgroup analyses were performed based on pregnancy trimester. Results: Five published studies were included in the systematic review and meta-analysis. There was an increase in the risk of preeclampsia with a 1% increase of HbA1c during pregnancy (OR = 1.38; 95% CI 1.26–1.52, I2=0.0%). When analyses were performed based on pregnancy trimester to estimate the risk of preeclampsia with a 1% increase of HbA1c, pooled OR estimates were 1.37 (95% CI 1.24–1.51, I2=0.0%) for the first trimester and 1.67 (95% CI 1.44–1.93, I2=0.0%) for the second/third trimester. Conclusion: HbA1c is a reliable predictor of preeclampsia in type 1 diabetic pregnant women. Our findings highlight the importance of including HbA1c measurements in the first antenatal visit to control the risk of preeclampsia in pregnant women. Systematic review registration: PROSPERO: CRD42017058394. © 2018
dc.language.isoen
dc.publisherElsevier B.V.
dc.subjectHbA1c
dc.subjectPreeclampsia
dc.subjectPregnancy
dc.subjectType 1 diabetes mellitus
dc.subjecthemoglobin A1c
dc.subjectbiological marker
dc.subjectglycosylated hemoglobin
dc.subjectArticle
dc.subjectfirst trimester pregnancy
dc.subjecthuman
dc.subjectinsulin dependent diabetes mellitus
dc.subjectmeta analysis
dc.subjectodds ratio
dc.subjectprediction
dc.subjectpreeclampsia
dc.subjectpregnancy
dc.subjectpriority journal
dc.subjectreliability
dc.subjectrisk assessment
dc.subjectsecond trimester pregnancy
dc.subjectsystematic review
dc.subjectthird trimester pregnancy
dc.subjectblood
dc.subjectfemale
dc.subjectmetabolism
dc.subjectpredictive value
dc.subjectpreeclampsia
dc.subjectpregnancy
dc.subjectpregnancy diabetes mellitus
dc.subjectprenatal diagnosis
dc.subjectBiomarkers
dc.subjectDiabetes Mellitus, Type 1
dc.subjectFemale
dc.subjectGlycated Hemoglobin A
dc.subjectHumans
dc.subjectPre-Eclampsia
dc.subjectPredictive Value of Tests
dc.subjectPregnancy
dc.subjectPregnancy in Diabetics
dc.subjectPrenatal Diagnosis
dc.titleGlycated haemoglobin A1c as a predictor of preeclampsia in type 1 diabetic pregnant women: A systematic review and meta-analysis
dc.typeArticle


Ficheros en el ítem

Thumbnail
Nombre:
item_2-s2.0-85050892881.pdf
Tamaño:
3.458Kb
Formato:
PDF
Ver/

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem