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Inflammatory markers IL-1β and RANK-L assessment after non-vital bleaching: A 3-month follow-up
dc.contributor.author | Bersezio C. | |
dc.contributor.author | Sánchez F. | |
dc.contributor.author | Estay J. | |
dc.contributor.author | Ledezma P. | |
dc.contributor.author | Vernal R. | |
dc.contributor.author | Garlet G. | |
dc.contributor.author | Oliveira O.B. | |
dc.contributor.author | Fernández E. | |
dc.date.accessioned | 2020-09-02T22:13:09Z | |
dc.date.available | 2020-09-02T22:13:09Z | |
dc.date.issued | 2020 | |
dc.identifier | 10.1111/jerd.12557 | |
dc.identifier.citation | 32, 1, 119-126 | |
dc.identifier.issn | 14964155 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12728/3753 | |
dc.description | Objective: This study assessed IL-1β and RANK-L levels in vivo and color stability of non-vital teeth bleached using hydrogen (35%) and carbamide (37%) peroxides 3 months after treatment. Materials and Methods: Fifty teeth were randomly divided into two groups(n = 25):35% hydrogen peroxide (HP) or 37% carbamide peroxide (CP). Four sessions of intracoronal walking-bleach procedure were performed. IL-1β and RANK-L levels were assessed from gingival crevicular fluid samples (from three vestibular and three palatines sites) at eight different time-points: at the beginning of the study (baseline), after four sessions of intracanal bleaching, and at 1 week, 1 month, and 3 months posttreatment. The color variations were visually detected using Vita bleach shade guide (ΔSGU). Results: Significant increases of IL-1β and RANK-L levels were detected at all time-points (all P <.05) when comparing each time-point to baseline, and a high correlation (>0.8—Spearman) between variables. According the ΔSGU values, a color change of five for HP and four for CP were detected. Conclusions: Non-vital walking bleach technique promotes an increase in IL-1β and RANKL levels in periodontal tissues and also, it is maintained until the third-month posttreatment. Clinical Significance: The internal whitening of teeth increases the levels of cytokines associated with inflammation and bone resorption 3 months after the whitening procedure is finished; this should warn of possible harmful effects of this whitening technique. © 2019 Wiley Periodicals, Inc. | |
dc.language.iso | en | |
dc.publisher | Blackwell Publishing Ltd | |
dc.subject | biomarkers | |
dc.subject | double-blind study | |
dc.subject | hydrogen peroxide | |
dc.subject | RANK-L | |
dc.subject | tooth bleaching | |
dc.subject | hydrogen peroxide | |
dc.subject | peroxide | |
dc.subject | tooth bleaching agent | |
dc.subject | urea | |
dc.subject | color | |
dc.subject | dental procedure | |
dc.subject | follow up | |
dc.subject | human | |
dc.subject | tooth discoloration | |
dc.subject | Color | |
dc.subject | Follow-Up Studies | |
dc.subject | Humans | |
dc.subject | Hydrogen Peroxide | |
dc.subject | Peroxides | |
dc.subject | Tooth Bleaching | |
dc.subject | Tooth Bleaching Agents | |
dc.subject | Tooth Discoloration | |
dc.subject | Urea | |
dc.title | Inflammatory markers IL-1β and RANK-L assessment after non-vital bleaching: A 3-month follow-up | |
dc.type | Article |