Investigación y Desarrollo: Envíos recientes
Mostrando ítems 1-20 de 5710
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Article
LINC00662 Promotes Aggressive Traits by Modulating OCT4 Expression through miR-335-5p in Gallbladder Cancer Cells (2024)
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)Long non-coding RNAs (lncRNAs) are nucleotide sequences that participate in different biological processes and are associated with different pathologies, including cancer. Long intergenic non-protein-coding RNA 662 (LINC00662) ... -
Article
Axonal and Glial PIEZO1 and PIEZO2 Immunoreactivity in Human Clitoral Krause’s Corpuscles (2024)
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)Krause’s corpuscles are typical of cutaneous mucous epithelia, like the lip vermillion or the glans clitoridis, and are associated with rapidly adapting low-threshold mechanoreceptors involved in gentle touch or vibration. ... -
Article
Involvement of the GH38 Family Exoglycosidase α-Mannosidase in Strawberry Fruit Ripening (2024)
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)Exoglycosidase enzymes hydrolyze the N-glycosylations of cell wall enzymes, releasing N-glycans that act as signal molecules and promote fruit ripening. Vesicular exoglycosidase α-mannosidase enzymes of the GH38 family (EC ... -
Article
The Water Management Impacts of Large-Scale Mining Operations: A Social and Environmental Perspective (2024)
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)This study investigates water consumption in two areas with limited water resources—the Salar de Atacama and Salar de Atacama-Vertiente Pacifico basins in Chile’s Antofagasta Region—with the aim of developing strategies ... -
Article
Association between the Anatomical Location of Glioblastoma and Its Evaluation with Clinical Considerations: A Systematic Review and Meta-Analysis (2024)
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)Background: Glioblastoma is a primary malignant brain tumor; it is aggressive with a high degree of malignancy and unfavorable prognosis and is the most common type of malignant brain tumor. Glioblastomas can be located ... -
Article
Deciphering the Molecular Interaction Process of Gallium Maltolate on SARS-CoV-2 Main and Papain-Like Proteases: A Theoretical Study (2024)
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)This study explored the inhibitory potential of gallium maltolate against severe acute respiratory syndrome coronavirus 2 and main and papain-like proteases. Computational methods, including density functional theory and ... -
Article
Morphological Characteristics of the Double Mental Foramen and Its Relevance in Clinical Practice: An Observational Study (2024)
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)The mental foramen (MF) is an opening found bilaterally on the anterolateral aspect of the mandible; it can be round or oval and have different diameters. One of the anatomical variants of the jaw is the presence of an ... -
Article
The Role of Family Functionality and Its Relationship with Psychological Well-Being and Emotional Intelligence in High School Students (2024)
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)Adolescence is acknowledged as a critical transition stage in human development, during which factors such as family environment, psychological well-being, and emotional competencies are deemed crucial for optimal growth. ... -
Article
Key driving forces of energy consumption in a higher education institution using the LMDI approach: The case of the Universidad Autónoma de Chile. (2024)
(Elsevier Ltd, 2024)Energy consumption in universities is a crucial issue as they aim to balance growing operational demands with environmental sustainability. This study employs the Logarithmic Mean Divisia Index method to assess energy ... -
Article
Antimicrobial Activity of Drimanic Sesquiterpene Compounds from Drimys winteri against Multiresistant Microorganisms (2024)
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)In this work, a group of ten sesquiterpene drimanes, including polygodial (1), isopolygodial (2), and drimenol (3) obtained from the bark of Drimys winteri F. and seven synthetic derivatives, were tested in vitro against ... -
Article
Evaluation of the Biological Activities of Peptides from Epidermal Mucus of Marine Fish Species from Chilean Aquaculture (2024)
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)The skin of fish is a physicochemical barrier that is characterized by being formed by cells that secrete molecules responsible for the first defense against pathogenic organisms. In this study, the biological activity of ... -
Article
Effect of Exercise Prior to Sedentary Behavior on Vascular Health Parameters: A Systematic Review and Meta-Analysis of Crossover Trials (2024)
(Springer Science and Business Media Deutschland GmbH, 2024)Background: Sedentary behavior has been shown to negatively affect parameters of endothelial function and central hemodynamics, both of which are closely associated with vascular health. Exercise prior to sedentary behavior ... -
Article
Change and social recomposition in elite universities and programs in Chile (2009–2019) (2024)
(Universidad Austral de Chile, 2023)This work studies students’ socioeconomic composition in elite universities and programs in Chile between 2009 and 2019. To this end, we analyze eight highly prestigious and selective universities, focusing on three aspects: ... -
Article
Study in adulthood: Perceptions of a motivational challenge (2024)
(Universidad Austral de Chile, 2023)Education as a social right must be permanent, inclusive, participatory and motivating. Based on what has been stated, this study aims to determine if there is interest in adults in finishing their Basic Education studies, ... -
Article
How do Protected Areas Contribute to Human Well-Being? Multiple Mechanisms Perceived by Stakeholders in Chile (2024)
(Springer, 2024)Biodiversity conservation in designated protected areas reshapes the ways in which people interact with their ecosystems and each other, providing changes in their opportunities to satisfy different aspects of their ... -
Article
A Chaotic Maps-Based Privacy-Preserving Distributed Deep Learning for Incomplete and Non-IID Datasets (2024)
(IEEE Computer Society, 2024)Federated Learning is a machine learning approach that enables the training of a deep learning model among several participants with sensitive data that wish to share their own knowledge without compromising the privacy ... -
Article
BASECOL2023 scientific content (2024)
(EDP Sciences, 2024)Context. The global context of making numerous data produced by researchers available requires collecting and organising the data, assigning meaningful metadata, and presenting the data in a meaningful and homogeneous way. ... -
Article
Racism and food delivery platforms: shaping migrants’ work experiences and future expectations in the United Kingdom and Chile (2024)
(Routledge, 2024)Recent studies have demonstrated that platform work is predominately undertaken by migrant workers. Drawing on a qualitative study of platform-based food delivery work in Chile and the United Kingdom, we examine how migrant ... -
Article
Targeting CCR3 with antagonist SB 328437 sensitizes 5‑fluorouracil‑resistant gastric cancer cells: Experimental evidence and computational insights (2024)
(Spandidos Publications, 2024)Gastric cancer (GC) ranks fifth globally in cancer diag‑ noses and third for cancer‑related deaths. Chemotherapy with 5‑fluorouracil (5‑FU), a primary treatment, faces challenges due to the development of chemoresistance. ... -
Article
Global prevalence and gender inequalities in at least 60 min of self-reported moderate-to-vigorous physical activity 1 or more days per week: An analysis with 707,616 adolescents (2024)
(Elsevier B.V., 2024)Background: Guidelines recommend that adolescents should accumulate an average of 60 min per day of moderate-to-vigorous physical activity (MVPA). However, using only this cut-off could hide important information. For ...