ListarInvestigación y Desarrollo por tema "Alzheimer´s disease"
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Dexibuprofen ameliorates peripheral and central risk factors associated with Alzheimer’s disease in metabolically stressed APPswe/PS1dE9 mice (2021)
(BioMed Central Ltd, 2021-12)Background: Several studies stablished a relationship between metabolic disturbances and Alzheimer´s disease (AD) where inflammation plays a pivotal role. However, mechanisms involved still remain unclear. In the present ... -
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The role of mitochondrial impairment in alzheimer´s disease neurodegeneration: The Tau connection (2020)
(Bentham Science Publishers, 2020)Accumulative evidence has shown that mitochondrial dysfunction plays a pivotal role in the pathogenesis of Alzheimer's disease (AD). Mitochondrial impairment actively contributes to the synaptic and cognitive failure that ...